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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK4
All Species:
15.15
Human Site:
S494
Identified Species:
30.3
UniProt:
Q96L34
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96L34
NP_113605.2
752
82520
S494
I
P
E
R
R
K
D
S
T
S
T
P
N
N
L
Chimpanzee
Pan troglodytes
XP_512745
736
81102
S479
I
P
E
R
R
K
D
S
T
S
T
P
N
N
L
Rhesus Macaque
Macaca mulatta
XP_001105523
666
73735
R446
K
T
E
E
G
G
D
R
G
A
P
G
L
A
L
Dog
Lupus familis
XP_541564
690
76525
P469
M
V
S
S
A
H
N
P
N
K
A
E
I
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIP4
752
82625
S494
I
P
E
R
R
K
D
S
T
S
T
P
N
N
L
Rat
Rattus norvegicus
Q8VHF0
797
88733
P490
I
P
E
R
K
K
S
P
A
V
P
S
S
N
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508081
736
82480
S482
I
P
E
R
K
K
S
S
T
V
P
S
N
N
T
Chicken
Gallus gallus
Q9IA88
798
88848
S511
S
S
D
S
C
L
T
S
S
S
N
D
S
S
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
Q698
Q
L
Q
R
L
R
I
Q
P
S
S
P
P
P
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
I829
K
E
S
K
P
S
M
I
H
Q
S
P
S
M
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
K292
P
D
T
V
E
Q
A
K
K
I
N
E
E
I
V
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
S413
L
D
T
F
L
S
Q
S
P
P
T
F
Q
Q
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
75.8
88.4
N.A.
97.6
60.4
N.A.
64.4
32.4
N.A.
29.3
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
100
94.4
77.9
89.3
N.A.
98.9
73.5
N.A.
77.3
50
N.A.
41.2
N.A.
N.A.
N.A.
46.9
N.A.
P-Site Identity:
100
100
20
0
N.A.
100
40
N.A.
60
13.3
N.A.
20
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
26.6
13.3
N.A.
100
53.3
N.A.
66.6
46.6
N.A.
40
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.5
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
9
0
9
9
9
0
0
9
9
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
9
0
0
0
34
0
0
0
0
9
0
0
0
% D
% Glu:
0
9
50
9
9
0
0
0
0
0
0
17
9
0
9
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
0
9
9
0
0
9
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% H
% Ile:
42
0
0
0
0
0
9
9
0
9
0
0
9
9
0
% I
% Lys:
17
0
0
9
17
42
0
9
9
9
0
0
0
0
0
% K
% Leu:
9
9
0
0
17
9
0
0
0
0
0
0
9
0
34
% L
% Met:
9
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
9
0
9
0
17
0
34
42
0
% N
% Pro:
9
42
0
0
9
0
0
17
17
9
25
42
9
17
9
% P
% Gln:
9
0
9
0
0
9
9
9
0
9
0
0
9
9
9
% Q
% Arg:
0
0
0
50
25
9
0
9
0
0
0
0
0
0
0
% R
% Ser:
9
9
17
17
0
17
17
50
9
42
17
17
25
9
0
% S
% Thr:
0
9
17
0
0
0
9
0
34
0
34
0
0
0
17
% T
% Val:
0
9
0
9
0
0
0
0
0
17
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _