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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARK4 All Species: 19.7
Human Site: T624 Identified Species: 39.39
UniProt: Q96L34 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96L34 NP_113605.2 752 82520 T624 T K L T S K L T R R V A D E P
Chimpanzee Pan troglodytes XP_512745 736 81102 T608 T K L T S K L T R R V A D E P
Rhesus Macaque Macaca mulatta XP_001105523 666 73735 T564 P E R R K D S T S T P N N L P
Dog Lupus familis XP_541564 690 76525 T587 C H L P W D Q T E T A P R L L
Cat Felis silvestris
Mouse Mus musculus Q8CIP4 752 82625 T624 T K L T S K L T R R V T D E P
Rat Rattus norvegicus Q8VHF0 797 88733 T666 S K L T S K L T R R L P T E Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508081 736 82480 T605 S K L T S K L T R R L P T E Y
Chicken Gallus gallus Q9IA88 798 88848 E646 S S S G S S R E G R N L L E E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 S914 G L L S P R H S L T G H A D P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 R981 F P R N T R N R Q T F H G K T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 V410 P R E I M N E V L K A L Q E L
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 A531 I A L K N L G A E W A K P S E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.8 75.8 88.4 N.A. 97.6 60.4 N.A. 64.4 32.4 N.A. 29.3 N.A. N.A. N.A. 34.8 N.A.
Protein Similarity: 100 94.4 77.9 89.3 N.A. 98.9 73.5 N.A. 77.3 50 N.A. 41.2 N.A. N.A. N.A. 46.9 N.A.
P-Site Identity: 100 100 13.3 13.3 N.A. 93.3 66.6 N.A. 66.6 20 N.A. 13.3 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 26.6 13.3 N.A. 93.3 80 N.A. 80 26.6 N.A. 40 N.A. N.A. N.A. 26.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.5 27.7 N.A.
Protein Similarity: N.A. N.A. N.A. 43.8 44.6 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 9 0 0 25 17 9 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 17 0 0 0 0 0 0 25 9 0 % D
% Glu: 0 9 9 0 0 0 9 9 17 0 0 0 0 59 17 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 9 0 0 9 0 0 9 0 9 0 9 0 9 0 0 % G
% His: 0 9 0 0 0 0 9 0 0 0 0 17 0 0 0 % H
% Ile: 9 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 42 0 9 9 42 0 0 0 9 0 9 0 9 0 % K
% Leu: 0 9 67 0 0 9 42 0 17 0 17 17 9 17 17 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 9 9 9 0 0 0 9 9 9 0 0 % N
% Pro: 17 9 0 9 9 0 0 0 0 0 9 25 9 0 42 % P
% Gln: 0 0 0 0 0 0 9 0 9 0 0 0 9 0 0 % Q
% Arg: 0 9 17 9 0 17 9 9 42 50 0 0 9 0 0 % R
% Ser: 25 9 9 9 50 9 9 9 9 0 0 0 0 9 0 % S
% Thr: 25 0 0 42 9 0 0 59 0 34 0 9 17 0 9 % T
% Val: 0 0 0 0 0 0 0 9 0 0 25 0 0 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _