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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARK4
All Species:
23.64
Human Site:
Y278
Identified Species:
47.27
UniProt:
Q96L34
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96L34
NP_113605.2
752
82520
Y278
G
K
Y
R
V
P
F
Y
M
S
T
D
C
E
S
Chimpanzee
Pan troglodytes
XP_512745
736
81102
Y263
G
K
Y
R
V
P
F
Y
M
S
T
D
C
E
S
Rhesus Macaque
Macaca mulatta
XP_001105523
666
73735
A237
K
F
R
Q
I
V
S
A
V
H
Y
C
H
Q
K
Dog
Lupus familis
XP_541564
690
76525
Y260
E
R
V
L
R
G
K
Y
R
V
P
F
Y
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIP4
752
82625
Y278
G
K
Y
R
V
P
F
Y
M
S
T
D
C
E
S
Rat
Rattus norvegicus
Q8VHF0
797
88733
Y275
G
K
Y
R
I
P
F
Y
M
S
T
D
C
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508081
736
82480
Y267
G
K
Y
R
I
P
F
Y
M
S
T
D
C
E
N
Chicken
Gallus gallus
Q9IA88
798
88848
F245
G
R
F
R
I
P
Y
F
M
S
E
D
C
E
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
F278
G
K
F
R
I
P
F
F
M
S
T
D
C
E
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
Y389
G
K
Y
R
I
P
F
Y
M
S
T
D
C
E
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
Q83
M
H
P
H
I
I
R
Q
Y
E
V
I
E
T
T
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
D204
G
L
S
N
I
M
T
D
G
N
F
L
K
T
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.8
75.8
88.4
N.A.
97.6
60.4
N.A.
64.4
32.4
N.A.
29.3
N.A.
N.A.
N.A.
34.8
N.A.
Protein Similarity:
100
94.4
77.9
89.3
N.A.
98.9
73.5
N.A.
77.3
50
N.A.
41.2
N.A.
N.A.
N.A.
46.9
N.A.
P-Site Identity:
100
100
0
13.3
N.A.
100
86.6
N.A.
86.6
53.3
N.A.
73.3
N.A.
N.A.
N.A.
86.6
N.A.
P-Site Similarity:
100
100
26.6
20
N.A.
100
100
N.A.
100
93.3
N.A.
93.3
N.A.
N.A.
N.A.
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27.5
27.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.8
44.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
67
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
67
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
9
9
0
9
67
0
% E
% Phe:
0
9
17
0
0
0
59
17
0
0
9
9
0
0
0
% F
% Gly:
75
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% G
% His:
0
9
0
9
0
0
0
0
0
9
0
0
9
0
0
% H
% Ile:
0
0
0
0
67
9
0
0
0
0
0
9
0
0
0
% I
% Lys:
9
59
0
0
0
0
9
0
0
0
0
0
9
0
9
% K
% Leu:
0
9
0
9
0
0
0
0
0
0
0
9
0
0
0
% L
% Met:
9
0
0
0
0
9
0
0
67
0
0
0
0
9
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
25
% N
% Pro:
0
0
9
0
0
67
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
9
0
0
0
0
0
9
0
% Q
% Arg:
0
17
9
67
9
0
9
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
9
0
0
0
9
0
0
67
0
0
0
0
42
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
59
0
0
17
17
% T
% Val:
0
0
9
0
25
9
0
0
9
9
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
50
0
0
0
9
59
9
0
9
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _