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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NSD1 All Species: 9.7
Human Site: S707 Identified Species: 30.48
UniProt: Q96L73 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96L73 NP_071900.2 2696 296652 S707 Q K P L I S N S H T D H L M G
Chimpanzee Pan troglodytes XP_001139598 2697 296769 S707 Q K P L I S N S H T D H L M G
Rhesus Macaque Macaca mulatta XP_001094467 2340 257842 N485 V D G L K L L N N M H E K T R
Dog Lupus familis XP_852438 2698 297039 S707 Q K S L I T N S H T D H L M D
Cat Felis silvestris
Mouse Mus musculus O88491 2588 284065 C678 Q T L L P L K C R Q P K F R S
Rat Rattus norvegicus NP_001100807 2381 262479 G526 S K S G K G E G L K L L N N M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_683890 2055 227753 S200 A K T E T Q S S H R L D A N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MT36 1427 159010
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 84.9 91.2 N.A. 80 74 N.A. N.A. N.A. N.A. 35.3 N.A. 20.7 N.A. N.A. N.A.
Protein Similarity: 100 99.7 85.5 94.6 N.A. 85.2 78.7 N.A. N.A. N.A. N.A. 50 N.A. 31.8 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 80 N.A. 13.3 6.6 N.A. N.A. N.A. N.A. 20 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 20 86.6 N.A. 13.3 6.6 N.A. N.A. N.A. N.A. 26.6 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % A
% Cys: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % C
% Asp: 0 13 0 0 0 0 0 0 0 0 38 13 0 0 13 % D
% Glu: 0 0 0 13 0 0 13 0 0 0 0 13 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % F
% Gly: 0 0 13 13 0 13 0 13 0 0 0 0 0 0 25 % G
% His: 0 0 0 0 0 0 0 0 50 0 13 38 0 0 0 % H
% Ile: 0 0 0 0 38 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 63 0 0 25 0 13 0 0 13 0 13 13 0 13 % K
% Leu: 0 0 13 63 0 25 13 0 13 0 25 13 38 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 13 0 0 0 38 13 % M
% Asn: 0 0 0 0 0 0 38 13 13 0 0 0 13 25 0 % N
% Pro: 0 0 25 0 13 0 0 0 0 0 13 0 0 0 0 % P
% Gln: 50 0 0 0 0 13 0 0 0 13 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 13 13 0 0 0 13 13 % R
% Ser: 13 0 25 0 0 25 13 50 0 0 0 0 0 0 13 % S
% Thr: 0 13 13 0 13 13 0 0 0 38 0 0 0 13 0 % T
% Val: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _