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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRMT6 All Species: 20.91
Human Site: S308 Identified Species: 38.33
UniProt: Q96LA8 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96LA8 NP_060607.2 375 41938 S308 S E K P L V L S T S P F H P A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082208 375 41889 S308 S E K P L V L S T S P F H P A
Dog Lupus familis XP_547254 376 41667 S309 A E K P L V L S T S P F H P V
Cat Felis silvestris
Mouse Mus musculus Q6NZB1 378 41848 S311 S E K P L V L S T S P F H P A
Rat Rattus norvegicus Q63009 353 40504 S286 K R T G F S T S P E S P Y T H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q68EZ3 340 37897 S273 G E K T V T L S T S P Y G E E
Zebra Danio Brachydanio rerio Q6NWG4 349 39232 E283 S T S P F K A E T H W K Q A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VH48 530 59709 S400 S S Q N V W L S T S P T A P L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795838 328 36645 D262 L T L S T S P D E P Y T H W R
Poplar Tree Populus trichocarpa XP_002310910 258 29074 V192 A T L Y M A P V T H P D R Y R
Maize Zea mays NP_001142360 403 44948 P311 R Q K S K K Q P S Q S L D E N
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q08A71 435 48253 S338 S S P A K N T S E T S I A S G
Baker's Yeast Sacchar. cerevisiae P38074 348 39768 T282 T G P H A P Y T H W K Q T I F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 89.3 N.A. 91.8 34.1 N.A. N.A. N.A. 54.6 52.7 N.A. 25.8 N.A. N.A. 39.7
Protein Similarity: 100 N.A. 99.7 93.6 N.A. 95.5 52.2 N.A. N.A. N.A. 70.4 70.1 N.A. 40.7 N.A. N.A. 55.4
P-Site Identity: 100 N.A. 100 86.6 N.A. 100 6.6 N.A. N.A. N.A. 46.6 20 N.A. 46.6 N.A. N.A. 6.6
P-Site Similarity: 100 N.A. 100 93.3 N.A. 100 13.3 N.A. N.A. N.A. 60 20 N.A. 60 N.A. N.A. 6.6
Percent
Protein Identity: 33.6 40.9 N.A. 40.4 33.3 N.A.
Protein Similarity: 47.4 55 N.A. 54.9 52 N.A.
P-Site Identity: 13.3 6.6 N.A. 13.3 0 N.A.
P-Site Similarity: 26.6 20 N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 8 8 8 8 0 0 0 0 0 16 8 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 8 0 0 0 8 8 0 0 % D
% Glu: 0 39 0 0 0 0 0 8 16 8 0 0 0 16 8 % E
% Phe: 0 0 0 0 16 0 0 0 0 0 0 31 0 0 8 % F
% Gly: 8 8 0 8 0 0 0 0 0 0 0 0 8 0 8 % G
% His: 0 0 0 8 0 0 0 0 8 16 0 0 39 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % I
% Lys: 8 0 47 0 16 16 0 0 0 0 8 8 0 0 0 % K
% Leu: 8 0 16 0 31 0 47 0 0 0 0 8 0 0 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 16 39 0 8 16 8 8 8 54 8 0 39 0 % P
% Gln: 0 8 8 0 0 0 8 0 0 8 0 8 8 0 0 % Q
% Arg: 8 8 0 0 0 0 0 0 0 0 0 0 8 0 16 % R
% Ser: 47 16 8 16 0 16 0 62 8 47 24 0 0 8 0 % S
% Thr: 8 24 8 8 8 8 16 8 62 8 0 16 8 8 0 % T
% Val: 0 0 0 0 16 31 0 8 0 0 0 0 0 0 16 % V
% Trp: 0 0 0 0 0 8 0 0 0 8 8 0 0 8 0 % W
% Tyr: 0 0 0 8 0 0 8 0 0 0 8 8 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _