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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MRGPRX4
All Species:
3.94
Human Site:
T175
Identified Species:
17.33
UniProt:
Q96LA9
Number Species:
5
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96LA9
NP_473373
322
36434
T175
A
D
S
S
W
C
E
T
S
D
F
I
P
V
A
Chimpanzee
Pan troglodytes
Q4QXX9
329
36858
F182
D
S
G
W
C
Q
T
F
D
L
I
T
A
A
W
Rhesus Macaque
Macaca mulatta
Q2LL16
322
36605
T175
A
D
S
V
W
C
E
T
S
D
F
I
T
I
A
Dog
Lupus familis
XP_542529
389
43356
A240
L
D
Y
G
W
C
R
A
F
D
F
I
T
A
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIP3
322
36791
D179
H
H
L
W
K
N
V
D
F
I
I
T
A
F
L
Rat
Rattus norvegicus
Q8R4G1
323
37056
V179
H
H
H
L
W
K
N
V
D
F
I
V
T
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62.3
82.9
48.5
N.A.
51.8
51
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
71.7
88.5
59.3
N.A.
68
69.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
80
40
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
86.6
40
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
0
0
0
17
0
0
0
0
34
50
34
% A
% Cys:
0
0
0
0
17
50
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
50
0
0
0
0
0
17
34
50
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
34
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
17
34
17
50
0
0
17
17
% F
% Gly:
0
0
17
17
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
34
34
17
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
17
50
50
0
17
0
% I
% Lys:
0
0
0
0
17
17
0
0
0
0
0
0
0
0
0
% K
% Leu:
17
0
17
17
0
0
0
0
0
17
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
17
17
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% P
% Gln:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% R
% Ser:
0
17
34
17
0
0
0
0
34
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
17
34
0
0
0
34
50
0
17
% T
% Val:
0
0
0
17
0
0
17
17
0
0
0
17
0
17
0
% V
% Trp:
0
0
0
34
67
0
0
0
0
0
0
0
0
0
17
% W
% Tyr:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _