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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IFT74
All Species:
22.73
Human Site:
S253
Identified Species:
41.67
UniProt:
Q96LB3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96LB3
NP_001092692.1
600
69239
S253
T
L
Q
Q
Q
L
D
S
Q
N
M
K
K
E
S
Chimpanzee
Pan troglodytes
XP_001153797
600
69221
S253
T
L
Q
Q
Q
L
D
S
Q
N
M
K
K
E
S
Rhesus Macaque
Macaca mulatta
XP_001105415
600
69424
S253
T
L
Q
Q
Q
L
D
S
Q
N
M
K
K
E
S
Dog
Lupus familis
XP_531964
600
69367
S253
T
L
Q
Q
Q
L
D
S
L
N
M
K
K
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKE9
600
69283
S253
T
L
Q
Q
Q
L
D
S
L
N
M
K
K
E
S
Rat
Rattus norvegicus
Q53UA7
898
105455
L493
M
D
E
H
R
L
K
L
Q
K
E
V
E
T
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505938
858
99477
T511
V
F
Q
Q
E
L
D
T
L
S
M
K
K
K
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PW73
1335
154049
L413
N
K
E
L
Q
A
E
L
V
N
G
K
L
L
T
Zebra Danio
Brachydanio rerio
NP_001002385
486
57187
R179
L
L
D
L
E
N
R
R
A
S
L
Q
A
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392873
429
50071
Y121
Q
I
Q
D
K
R
Y
Y
N
G
L
M
Q
L
K
Nematode Worm
Caenorhab. elegans
Q11102
1130
131467
G476
T
T
K
E
H
Y
E
G
L
L
L
K
E
R
Q
Sea Urchin
Strong. purpuratus
XP_789962
373
43924
L66
L
E
D
K
K
S
Q
L
I
A
E
E
Q
S
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32380
944
111763
F341
L
N
E
L
E
T
K
F
S
E
N
G
S
Q
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
94.8
90.8
N.A.
87.8
20.1
N.A.
48.2
N.A.
20
47.3
N.A.
N.A.
22.6
20.7
34.5
Protein Similarity:
100
99.3
96.8
94.6
N.A.
94
39
N.A.
56.8
N.A.
32.4
64.5
N.A.
N.A.
39.6
36.8
47.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
46.6
N.A.
20
13.3
N.A.
N.A.
6.6
13.3
0
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
33.3
N.A.
80
N.A.
40
40
N.A.
N.A.
33.3
46.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
8
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
16
8
0
0
47
0
0
0
0
0
0
0
8
% D
% Glu:
0
8
24
8
24
0
16
0
0
8
16
8
16
47
0
% E
% Phe:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
8
8
8
0
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
8
8
16
0
16
0
0
8
0
62
47
8
8
% K
% Leu:
24
47
0
24
0
54
0
24
31
8
24
0
8
16
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
47
8
0
0
0
% M
% Asn:
8
8
0
0
0
8
0
0
8
47
8
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
54
47
47
0
8
0
31
0
0
8
16
8
8
% Q
% Arg:
0
0
0
0
8
8
8
8
0
0
0
0
0
8
8
% R
% Ser:
0
0
0
0
0
8
0
39
8
16
0
0
8
8
47
% S
% Thr:
47
8
0
0
0
8
0
8
0
0
0
0
0
8
8
% T
% Val:
8
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
8
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _