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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IFT74 All Species: 22.42
Human Site: S411 Identified Species: 41.11
UniProt: Q96LB3 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96LB3 NP_001092692.1 600 69239 S411 I N R I E Q I S S I T N Q E L
Chimpanzee Pan troglodytes XP_001153797 600 69221 S411 I N R M E Q I S S I T N Q E L
Rhesus Macaque Macaca mulatta XP_001105415 600 69424 S411 I N R M K Q I S S I T N Q E L
Dog Lupus familis XP_531964 600 69367 S411 I N R M K Q I S S I T N Q E L
Cat Felis silvestris
Mouse Mus musculus Q8BKE9 600 69283 S411 I N R M K Q I S S I T N Q E L
Rat Rattus norvegicus Q53UA7 898 105455 R671 L H T L Q K L R M D L I R L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505938 858 99477 S669 I N R M K E I S C V T N Q D L
Chicken Gallus gallus
Frog Xenopus laevis Q9PW73 1335 154049 L822 L N Q V K L E L K H T N V T L
Zebra Danio Brachydanio rerio NP_001002385 486 57187 L309 S S V T A Q E L Q S M Q E D L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392873 429 50071 K251 D S M D S D T K E K Y D E L L
Nematode Worm Caenorhab. elegans Q11102 1130 131467 G765 N D M L D Q M G T I K D E L V
Sea Urchin Strong. purpuratus XP_789962 373 43924 D196 K E L A R M Q D D L S F K Q T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32380 944 111763 I603 I K Q K D E Q I S D L T Q N L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 94.8 90.8 N.A. 87.8 20.1 N.A. 48.2 N.A. 20 47.3 N.A. N.A. 22.6 20.7 34.5
Protein Similarity: 100 99.3 96.8 94.6 N.A. 94 39 N.A. 56.8 N.A. 32.4 64.5 N.A. N.A. 39.6 36.8 47.1
P-Site Identity: 100 93.3 86.6 86.6 N.A. 86.6 0 N.A. 60 N.A. 26.6 13.3 N.A. N.A. 6.6 13.3 0
P-Site Similarity: 100 100 100 100 N.A. 100 46.6 N.A. 93.3 N.A. 53.3 33.3 N.A. N.A. 26.6 66.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 8 8 0 8 16 8 0 8 8 16 0 16 0 16 0 % D
% Glu: 0 8 0 0 16 16 16 0 8 0 0 0 24 39 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 54 0 0 8 0 0 47 8 0 47 0 8 0 0 0 % I
% Lys: 8 8 0 8 39 8 0 8 8 8 8 0 8 0 0 % K
% Leu: 16 0 8 16 0 8 8 16 0 8 16 0 0 24 77 % L
% Met: 0 0 16 39 0 8 8 0 8 0 8 0 0 0 0 % M
% Asn: 8 54 0 0 0 0 0 0 0 0 0 54 0 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 16 0 8 54 16 0 8 0 0 8 54 8 8 % Q
% Arg: 0 0 47 0 8 0 0 8 0 0 0 0 8 0 0 % R
% Ser: 8 16 0 0 8 0 0 47 47 8 8 0 0 0 0 % S
% Thr: 0 0 8 8 0 0 8 0 8 0 54 8 0 8 8 % T
% Val: 0 0 8 8 0 0 0 0 0 8 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _