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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IFT74
All Species:
23.64
Human Site:
S435
Identified Species:
43.33
UniProt:
Q96LB3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96LB3
NP_001092692.1
600
69239
S435
K
S
T
E
V
Q
K
S
Q
S
T
A
Q
N
L
Chimpanzee
Pan troglodytes
XP_001153797
600
69221
S435
K
S
T
E
V
Q
K
S
Q
S
T
A
Q
N
L
Rhesus Macaque
Macaca mulatta
XP_001105415
600
69424
S435
K
S
T
E
V
Q
K
S
Q
S
T
A
R
N
L
Dog
Lupus familis
XP_531964
600
69367
S435
K
S
T
E
M
Q
K
S
Q
S
T
A
R
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKE9
600
69283
S435
K
S
T
E
M
Q
K
S
Q
T
T
A
R
N
L
Rat
Rattus norvegicus
Q53UA7
898
105455
R695
E
Y
N
K
R
R
E
R
E
L
H
R
K
H
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505938
858
99477
S693
K
S
R
E
M
E
K
S
R
S
T
N
R
N
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PW73
1335
154049
N846
L
K
N
K
E
E
K
N
A
S
M
L
K
L
L
Zebra Danio
Brachydanio rerio
NP_001002385
486
57187
L333
S
Q
S
T
A
K
G
L
N
S
E
S
E
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392873
429
50071
L275
A
N
E
L
Q
Q
K
L
D
E
L
Y
K
E
Q
Nematode Worm
Caenorhab. elegans
Q11102
1130
131467
L789
S
A
K
T
A
Q
L
L
E
S
N
T
V
E
S
Sea Urchin
Strong. purpuratus
XP_789962
373
43924
G220
S
G
L
T
G
E
S
G
R
L
Q
M
D
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32380
944
111763
Y627
L
K
S
I
I
D
R
Y
K
K
D
F
N
Q
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
94.8
90.8
N.A.
87.8
20.1
N.A.
48.2
N.A.
20
47.3
N.A.
N.A.
22.6
20.7
34.5
Protein Similarity:
100
99.3
96.8
94.6
N.A.
94
39
N.A.
56.8
N.A.
32.4
64.5
N.A.
N.A.
39.6
36.8
47.1
P-Site Identity:
100
100
93.3
86.6
N.A.
80
0
N.A.
60
N.A.
20
13.3
N.A.
N.A.
13.3
13.3
0
P-Site Similarity:
100
100
100
100
N.A.
100
53.3
N.A.
86.6
N.A.
46.6
40
N.A.
N.A.
26.6
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
16
0
0
0
8
0
0
39
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
0
0
8
0
8
0
8
0
0
% D
% Glu:
8
0
8
47
8
24
8
0
16
8
8
0
8
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
8
0
0
8
0
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% H
% Ile:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
47
16
8
16
0
8
62
0
8
8
0
0
24
0
0
% K
% Leu:
16
0
8
8
0
0
8
24
0
16
8
8
0
16
70
% L
% Met:
0
0
0
0
24
0
0
0
0
0
8
8
0
0
0
% M
% Asn:
0
8
16
0
0
0
0
8
8
0
8
8
8
47
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
8
54
0
0
39
0
8
0
16
8
16
% Q
% Arg:
0
0
8
0
8
8
8
8
16
0
0
8
31
8
0
% R
% Ser:
24
47
16
0
0
0
8
47
0
62
0
8
0
0
8
% S
% Thr:
0
0
39
24
0
0
0
0
0
8
47
8
0
0
0
% T
% Val:
0
0
0
0
24
0
0
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
8
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _