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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IFT74
All Species:
17.88
Human Site:
S492
Identified Species:
32.78
UniProt:
Q96LB3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96LB3
NP_001092692.1
600
69239
S492
N
D
L
P
A
L
K
S
S
G
E
E
K
I
K
Chimpanzee
Pan troglodytes
XP_001153797
600
69221
S492
N
D
L
P
A
L
K
S
S
G
E
E
K
I
K
Rhesus Macaque
Macaca mulatta
XP_001105415
600
69424
S492
N
D
L
P
A
L
K
S
S
G
E
E
K
K
K
Dog
Lupus familis
XP_531964
600
69367
S492
N
D
L
P
A
L
K
S
A
G
E
E
K
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKE9
600
69283
S492
S
D
L
A
A
L
K
S
S
A
E
E
K
K
K
Rat
Rattus norvegicus
Q53UA7
898
105455
K751
V
T
P
K
N
E
H
K
A
I
L
K
T
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505938
858
99477
M750
G
D
L
M
S
L
K
M
S
G
E
E
N
R
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q9PW73
1335
154049
N962
D
Q
L
L
K
D
R
N
W
E
L
K
Q
R
A
Zebra Danio
Brachydanio rerio
NP_001002385
486
57187
R388
L
R
A
A
G
E
Q
R
K
T
H
L
Q
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392873
429
50071
E330
I
S
P
E
E
E
K
E
K
L
L
Q
K
I
K
Nematode Worm
Caenorhab. elegans
Q11102
1130
131467
T847
K
E
R
E
V
E
L
T
G
M
R
T
K
L
D
Sea Urchin
Strong. purpuratus
XP_789962
373
43924
Q275
D
Q
K
K
K
K
L
Q
E
D
K
I
T
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32380
944
111763
W720
D
E
M
D
K
E
K
W
N
L
Q
E
S
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
94.8
90.8
N.A.
87.8
20.1
N.A.
48.2
N.A.
20
47.3
N.A.
N.A.
22.6
20.7
34.5
Protein Similarity:
100
99.3
96.8
94.6
N.A.
94
39
N.A.
56.8
N.A.
32.4
64.5
N.A.
N.A.
39.6
36.8
47.1
P-Site Identity:
100
100
93.3
86.6
N.A.
73.3
6.6
N.A.
60
N.A.
6.6
0
N.A.
N.A.
26.6
6.6
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
26.6
N.A.
66.6
N.A.
40
20
N.A.
N.A.
33.3
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
16
39
0
0
0
16
8
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
47
0
8
0
8
0
0
0
8
0
0
0
0
8
% D
% Glu:
0
16
0
16
8
39
0
8
8
8
47
54
0
8
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
0
0
8
39
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
0
8
0
24
0
% I
% Lys:
8
0
8
16
24
8
62
8
16
0
8
16
54
31
62
% K
% Leu:
8
0
54
8
0
47
16
0
0
16
24
8
0
24
0
% L
% Met:
0
0
8
8
0
0
0
8
0
8
0
0
0
0
0
% M
% Asn:
31
0
0
0
8
0
0
8
8
0
0
0
8
0
0
% N
% Pro:
0
0
16
31
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
16
0
0
0
0
8
8
0
0
8
8
16
0
0
% Q
% Arg:
0
8
8
0
0
0
8
8
0
0
8
0
0
16
0
% R
% Ser:
8
8
0
0
8
0
0
39
39
0
0
0
8
0
0
% S
% Thr:
0
8
0
0
0
0
0
8
0
8
0
8
16
0
0
% T
% Val:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _