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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNOT6L All Species: 34.24
Human Site: S395 Identified Species: 53.81
UniProt: Q96LI5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96LI5 NP_653172.2 555 63001 S395 K A S S R P G S P T A D P N S
Chimpanzee Pan troglodytes XP_523084 795 86793 S635 K A S S R P G S P T A D P N S
Rhesus Macaque Macaca mulatta XP_001092697 550 62412 S390 K A S S R P G S P T A D P N S
Dog Lupus familis XP_544939 550 62442 S390 K A S S R P G S P T A D P N S
Cat Felis silvestris
Mouse Mus musculus Q8VEG6 555 63005 S395 K A S S R P G S P T A D P N S
Rat Rattus norvegicus NP_001013878 557 63285 S396 K A S R S L K S S V L G E C G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506990 606 68333 S446 K A S S R P G S P T T D L N S
Chicken Gallus gallus XP_420472 549 62237 S389 K A S S R P G S P T A D P N S
Frog Xenopus laevis Q6IR85 550 62739 S390 K A A C R P G S P T P D P N S
Zebra Danio Brachydanio rerio A2BHJ4 559 63359 S390 S G S I N S S S P T S E T S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732965 552 63223 I374 E F C D V K L I Q T M M L S N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001023608 597 67557 I389 L V V A T A H I H W D P E F C
Sea Urchin Strong. purpuratus XP_779942 577 65769 M395 V K L I Q T M M L M N E L K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W0Z9 602 66743 E441 H T L L K G L E K I A A S A D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9C2R2 793 88733 L590 K Y V R W Q P L K D K R G I Q
Conservation
Percent
Protein Identity: 100 69.8 99 98.9 N.A. 98 77.7 N.A. 90 95.5 88.4 82.4 N.A. 57.6 N.A. 47.7 55.9
Protein Similarity: 100 69.8 99 98.9 N.A. 99 87 N.A. 90.5 97.6 96.4 91 N.A. 73.3 N.A. 65.1 71.2
P-Site Identity: 100 100 100 100 N.A. 100 26.6 N.A. 86.6 100 80 33.3 N.A. 6.6 N.A. 0 0
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. 86.6 100 86.6 53.3 N.A. 26.6 N.A. 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 26.4 N.A. 25
Protein Similarity: N.A. N.A. N.A. 43.3 N.A. 39.3
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 60 7 7 0 7 0 0 0 0 47 7 0 7 0 % A
% Cys: 0 0 7 7 0 0 0 0 0 0 0 0 0 7 7 % C
% Asp: 0 0 0 7 0 0 0 0 0 7 7 54 0 0 7 % D
% Glu: 7 0 0 0 0 0 0 7 0 0 0 14 14 0 0 % E
% Phe: 0 7 0 0 0 0 0 0 0 0 0 0 0 7 0 % F
% Gly: 0 7 0 0 0 7 54 0 0 0 0 7 7 0 7 % G
% His: 7 0 0 0 0 0 7 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 14 0 0 0 14 0 7 0 0 0 7 0 % I
% Lys: 67 7 0 0 7 7 7 0 14 0 7 0 0 7 7 % K
% Leu: 7 0 14 7 0 7 14 7 7 0 7 0 20 0 0 % L
% Met: 0 0 0 0 0 0 7 7 0 7 7 7 0 0 0 % M
% Asn: 0 0 0 0 7 0 0 0 0 0 7 0 0 54 7 % N
% Pro: 0 0 0 0 0 54 7 0 60 0 7 7 47 0 0 % P
% Gln: 0 0 0 0 7 7 0 0 7 0 0 0 0 0 7 % Q
% Arg: 0 0 0 14 54 0 0 0 0 0 0 7 0 0 0 % R
% Ser: 7 0 60 47 7 7 7 67 7 0 7 0 7 14 60 % S
% Thr: 0 7 0 0 7 7 0 0 0 67 7 0 7 0 0 % T
% Val: 7 7 14 0 7 0 0 0 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _