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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNOT6L All Species: 42.42
Human Site: S417 Identified Species: 66.67
UniProt: Q96LI5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96LI5 NP_653172.2 555 63001 S417 D L N S L P D S G V V E Y L S
Chimpanzee Pan troglodytes XP_523084 795 86793 S657 D L N S L P D S G V V E Y L S
Rhesus Macaque Macaca mulatta XP_001092697 550 62412 S412 D L N S L P D S G V V E Y L S
Dog Lupus familis XP_544939 550 62442 S412 D L N S L P D S G V V E Y L S
Cat Felis silvestris
Mouse Mus musculus Q8VEG6 555 63005 S417 D L N S L P D S G V V E Y L S
Rat Rattus norvegicus NP_001013878 557 63285 D418 A D L N S L P D S G V V E Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506990 606 68333 S468 D L N S L P D S G V V E Y L S
Chicken Gallus gallus XP_420472 549 62237 S411 D L N S L P D S G V V E Y L S
Frog Xenopus laevis Q6IR85 550 62739 S412 D L N S L L D S G V V E Y L T
Zebra Danio Brachydanio rerio A2BHJ4 559 63359 S412 D L N S L P D S G V V E Y L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732965 552 63223 P396 E A S H S F R P G H K N D S N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001023608 597 67557 S411 M M L T H E V S R V L E E V S
Sea Urchin Strong. purpuratus XP_779942 577 65769 S417 S F R P G G D S G T I P L V M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W0Z9 602 66743 S463 D F N T V P A S A P H T L L A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9C2R2 793 88733 E612 E S D I P K P E M P E P G P S
Conservation
Percent
Protein Identity: 100 69.8 99 98.9 N.A. 98 77.7 N.A. 90 95.5 88.4 82.4 N.A. 57.6 N.A. 47.7 55.9
Protein Similarity: 100 69.8 99 98.9 N.A. 99 87 N.A. 90.5 97.6 96.4 91 N.A. 73.3 N.A. 65.1 71.2
P-Site Identity: 100 100 100 100 N.A. 100 6.6 N.A. 100 100 86.6 100 N.A. 6.6 N.A. 26.6 20
P-Site Similarity: 100 100 100 100 N.A. 100 13.3 N.A. 100 100 93.3 100 N.A. 26.6 N.A. 53.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 26.4 N.A. 25
Protein Similarity: N.A. N.A. N.A. 43.3 N.A. 39.3
P-Site Identity: N.A. N.A. N.A. 33.3 N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 0 0 7 0 7 0 0 0 0 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 67 7 7 0 0 0 67 7 0 0 0 0 7 0 0 % D
% Glu: 14 0 0 0 0 7 0 7 0 0 7 67 14 0 0 % E
% Phe: 0 14 0 0 0 7 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 7 0 0 74 7 0 0 7 0 0 % G
% His: 0 0 0 7 7 0 0 0 0 7 7 0 0 0 0 % H
% Ile: 0 0 0 7 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 0 0 0 0 0 7 0 0 0 0 7 0 0 0 0 % K
% Leu: 0 60 14 0 60 14 0 0 0 0 7 0 14 67 7 % L
% Met: 7 7 0 0 0 0 0 0 7 0 0 0 0 0 7 % M
% Asn: 0 0 67 7 0 0 0 0 0 0 0 7 0 0 7 % N
% Pro: 0 0 0 7 7 60 14 7 0 14 0 14 0 7 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 0 0 0 7 0 7 0 0 0 0 0 0 % R
% Ser: 7 7 7 60 14 0 0 80 7 0 0 0 0 7 67 % S
% Thr: 0 0 0 14 0 0 0 0 0 7 0 7 0 0 7 % T
% Val: 0 0 0 0 7 0 7 0 0 67 67 7 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 60 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _