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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CNOT6L
All Species:
48.48
Human Site:
Y493
Identified Species:
76.19
UniProt:
Q96LI5
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96LI5
NP_653172.2
555
63001
Y493
G
V
I
D
Y
I
F
Y
S
K
T
H
M
N
V
Chimpanzee
Pan troglodytes
XP_523084
795
86793
Y733
G
V
I
D
Y
I
F
Y
S
K
T
H
M
N
V
Rhesus Macaque
Macaca mulatta
XP_001092697
550
62412
Y488
G
V
I
D
Y
I
F
Y
S
K
T
H
M
N
V
Dog
Lupus familis
XP_544939
550
62442
Y488
G
V
I
D
Y
I
F
Y
S
K
T
H
M
N
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VEG6
555
63005
Y493
G
V
I
D
Y
I
F
Y
S
K
T
H
M
N
V
Rat
Rattus norvegicus
NP_001013878
557
63285
Y495
G
I
I
D
Y
I
F
Y
S
K
P
Q
L
N
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506990
606
68333
Y544
G
V
I
D
Y
I
F
Y
S
K
T
H
M
N
V
Chicken
Gallus gallus
XP_420472
549
62237
Y487
G
V
I
D
Y
I
F
Y
S
N
T
H
M
N
V
Frog
Xenopus laevis
Q6IR85
550
62739
Y488
G
V
I
D
Y
I
F
Y
S
K
T
H
M
D
V
Zebra Danio
Brachydanio rerio
A2BHJ4
559
63359
F488
G
V
I
D
Y
I
F
F
S
K
T
H
M
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_732965
552
63223
Y490
G
I
I
D
Y
I
F
Y
T
K
T
G
M
V
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023608
597
67557
A514
G
M
I
D
Y
I
F
A
T
P
Q
S
L
A
R
Sea Urchin
Strong. purpuratus
XP_779942
577
65769
Y506
G
T
I
D
Y
I
F
Y
S
R
Q
A
M
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8W0Z9
602
66743
Y549
G
T
L
D
Y
I
F
Y
T
A
D
T
L
T
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q9C2R2
793
88733
Y711
E
V
I
D
Y
I
W
Y
S
T
N
T
L
E
V
Conservation
Percent
Protein Identity:
100
69.8
99
98.9
N.A.
98
77.7
N.A.
90
95.5
88.4
82.4
N.A.
57.6
N.A.
47.7
55.9
Protein Similarity:
100
69.8
99
98.9
N.A.
99
87
N.A.
90.5
97.6
96.4
91
N.A.
73.3
N.A.
65.1
71.2
P-Site Identity:
100
100
100
100
N.A.
100
66.6
N.A.
100
93.3
93.3
86.6
N.A.
66.6
N.A.
40
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
80
N.A.
100
93.3
100
100
N.A.
80
N.A.
60
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
26.4
N.A.
25
Protein Similarity:
N.A.
N.A.
N.A.
43.3
N.A.
39.3
P-Site Identity:
N.A.
N.A.
N.A.
46.6
N.A.
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
7
0
7
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
100
0
0
0
0
0
0
7
0
0
7
0
% D
% Glu:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
94
7
0
0
0
0
0
0
0
% F
% Gly:
94
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% H
% Ile:
0
14
94
0
0
100
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
67
0
0
0
0
0
% K
% Leu:
0
0
7
0
0
0
0
0
0
0
0
0
27
0
0
% L
% Met:
0
7
0
0
0
0
0
0
0
0
0
0
74
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
7
7
0
0
54
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
7
7
0
0
0
7
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
14
7
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% R
% Ser:
0
0
0
0
0
0
0
0
80
0
0
7
0
14
0
% S
% Thr:
0
14
0
0
0
0
0
0
20
7
67
14
0
7
7
% T
% Val:
0
67
0
0
0
0
0
0
0
0
0
0
0
7
80
% V
% Trp:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
100
0
0
87
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _