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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CNOT6L All Species: 44.24
Human Site: Y83 Identified Species: 69.52
UniProt: Q96LI5 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96LI5 NP_653172.2 555 63001 Y83 A K L H N L V Y L D L S S N K
Chimpanzee Pan troglodytes XP_523084 795 86793 Y323 A K L H N L V Y L D L S S N K
Rhesus Macaque Macaca mulatta XP_001092697 550 62412 Y78 A K L H N L V Y L D L S S N K
Dog Lupus familis XP_544939 550 62442 Y78 A K L H N L V Y L D L S S N K
Cat Felis silvestris
Mouse Mus musculus Q8VEG6 555 63005 Y83 A K L H N L V Y L D L S S N K
Rat Rattus norvegicus NP_001013878 557 63285 Y78 A K L H N L V Y L D L S H N Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506990 606 68333 Y134 A K L H N L V Y L D L S S N K
Chicken Gallus gallus XP_420472 549 62237 Y78 A K L H N L V Y L D L S S N K
Frog Xenopus laevis Q6IR85 550 62739 Y78 A K L H N L V Y L D L S S N K
Zebra Danio Brachydanio rerio A2BHJ4 559 63359 Y78 A K L P H L V Y L N L S S N K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732965 552 63223 T86 G M L T S L R T L D L S S N K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001023608 597 67557 M105 A Q L T N L T M L D I S N N K
Sea Urchin Strong. purpuratus XP_779942 577 65769 K103 C Q L T H L I K L D L S Y N K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8W0Z9 602 66743 T145 L S T S V S L T N G S S S V Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9C2R2 793 88733 I292 G K L R H L K I L E A S N N L
Conservation
Percent
Protein Identity: 100 69.8 99 98.9 N.A. 98 77.7 N.A. 90 95.5 88.4 82.4 N.A. 57.6 N.A. 47.7 55.9
Protein Similarity: 100 69.8 99 98.9 N.A. 99 87 N.A. 90.5 97.6 96.4 91 N.A. 73.3 N.A. 65.1 71.2
P-Site Identity: 100 100 100 100 N.A. 100 86.6 N.A. 100 100 100 80 N.A. 60 N.A. 60 53.3
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 100 100 100 93.3 N.A. 66.6 N.A. 80 73.3
Percent
Protein Identity: N.A. N.A. N.A. 26.4 N.A. 25
Protein Similarity: N.A. N.A. N.A. 43.3 N.A. 39.3
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. 40
P-Site Similarity: N.A. N.A. N.A. 20 N.A. 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 74 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 80 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 14 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % G
% His: 0 0 0 60 20 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 0 0 0 0 0 0 7 7 0 0 7 0 0 0 0 % I
% Lys: 0 74 0 0 0 0 7 7 0 0 0 0 0 0 80 % K
% Leu: 7 0 94 0 0 94 7 0 94 0 80 0 0 0 7 % L
% Met: 0 7 0 0 0 0 0 7 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 67 0 0 0 7 7 0 0 14 94 0 % N
% Pro: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 7 % Q
% Arg: 0 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % R
% Ser: 0 7 0 7 7 7 0 0 0 0 7 100 74 0 0 % S
% Thr: 0 0 7 20 0 0 7 14 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 7 0 67 0 0 0 0 0 0 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 67 0 0 0 0 7 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _