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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS1
All Species:
25.76
Human Site:
S190
Identified Species:
56.67
UniProt:
Q96LJ7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96LJ7
NP_001129522.1
313
33909
S190
R
H
G
V
S
C
V
S
L
W
P
G
I
V
Q
Chimpanzee
Pan troglodytes
XP_001169595
313
33804
S190
R
H
G
V
S
C
V
S
L
W
P
G
I
V
Q
Rhesus Macaque
Macaca mulatta
XP_001113707
313
34036
S190
R
H
G
V
S
Y
V
S
L
W
P
G
I
V
Q
Dog
Lupus familis
XP_537393
296
32202
S173
R
H
G
V
S
Y
V
S
L
W
P
G
M
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q99L04
313
33987
S190
R
H
G
V
S
Y
V
S
L
W
P
G
L
V
Q
Rat
Rattus norvegicus
Q4V8F9
524
58325
Q308
L
Q
E
Q
P
Q
L
Q
E
Q
P
Q
L
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520394
294
31581
R174
R
L
M
V
P
A
G
R
G
L
I
V
V
I
S
Chicken
Gallus gallus
Q8JIS3
246
26149
A132
I
A
Q
G
L
P
G
A
I
V
N
V
S
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002205
310
33871
S188
K
R
G
V
A
S
V
S
L
W
P
G
A
V
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21929
251
27201
S137
V
D
R
Q
I
K
G
S
I
V
N
I
S
S
Q
Sea Urchin
Strong. purpuratus
XP_797581
322
34924
S198
K
H
G
V
A
A
I
S
L
W
P
G
A
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.6
96.4
77.9
N.A.
82.7
20.2
N.A.
38.6
23.9
N.A.
58.4
N.A.
N.A.
N.A.
22
50.6
Protein Similarity:
100
93.9
98
84.9
N.A.
91
32.2
N.A.
51.4
40.8
N.A.
77
N.A.
N.A.
N.A.
38
69.8
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
6.6
N.A.
13.3
6.6
N.A.
66.6
N.A.
N.A.
N.A.
13.3
60
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
26.6
N.A.
26.6
20
N.A.
80
N.A.
N.A.
N.A.
20
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
19
19
0
10
0
0
0
0
19
0
0
% A
% Cys:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
64
10
0
0
28
0
10
0
0
64
0
0
0
% G
% His:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
10
0
10
0
19
0
10
10
28
10
0
% I
% Lys:
19
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% K
% Leu:
10
10
0
0
10
0
10
0
64
10
0
0
19
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
19
0
0
0
0
% N
% Pro:
0
0
0
0
19
10
0
0
0
0
73
0
0
0
0
% P
% Gln:
0
10
10
19
0
10
0
10
0
10
0
10
0
10
73
% Q
% Arg:
55
10
10
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
46
10
0
73
0
0
0
0
19
19
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
73
0
0
55
0
0
19
0
19
10
64
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _