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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS1
All Species:
22.42
Human Site:
Y133
Identified Species:
49.33
UniProt:
Q96LJ7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96LJ7
NP_001129522.1
313
33909
Y133
G
H
Y
F
C
S
V
Y
G
A
R
L
M
V
P
Chimpanzee
Pan troglodytes
XP_001169595
313
33804
Y133
G
H
Y
F
C
S
V
Y
G
A
R
L
M
V
P
Rhesus Macaque
Macaca mulatta
XP_001113707
313
34036
Y133
G
H
Y
F
C
S
V
Y
G
A
R
L
M
V
P
Dog
Lupus familis
XP_537393
296
32202
G127
L
M
V
P
A
G
Q
G
L
I
V
V
I
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99L04
313
33987
Y133
G
H
Y
L
C
S
V
Y
G
A
R
L
M
V
P
Rat
Rattus norvegicus
Q4V8F9
524
58325
T169
F
K
Q
H
C
A
Y
T
I
A
K
Y
G
M
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520394
294
31581
P122
G
G
W
W
L
Q
A
P
R
R
E
P
T
L
R
Chicken
Gallus gallus
Q8JIS3
246
26149
A86
F
E
L
L
V
N
N
A
A
V
A
M
L
Q
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002205
310
33871
Y131
G
H
Y
F
C
S
V
Y
A
A
R
L
M
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21929
251
27201
A91
I
H
G
L
V
N
N
A
G
I
A
T
N
H
A
Sea Urchin
Strong. purpuratus
XP_797581
322
34924
Y141
N
H
Y
I
C
S
V
Y
A
A
K
L
M
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.6
96.4
77.9
N.A.
82.7
20.2
N.A.
38.6
23.9
N.A.
58.4
N.A.
N.A.
N.A.
22
50.6
Protein Similarity:
100
93.9
98
84.9
N.A.
91
32.2
N.A.
51.4
40.8
N.A.
77
N.A.
N.A.
N.A.
38
69.8
P-Site Identity:
100
100
100
0
N.A.
93.3
13.3
N.A.
6.6
6.6
N.A.
86.6
N.A.
N.A.
N.A.
13.3
73.3
P-Site Similarity:
100
100
100
13.3
N.A.
93.3
33.3
N.A.
26.6
26.6
N.A.
86.6
N.A.
N.A.
N.A.
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
10
19
28
64
19
0
0
0
19
% A
% Cys:
0
0
0
0
64
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
19
0
0
37
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
55
10
10
0
0
10
0
10
46
0
0
0
10
0
0
% G
% His:
0
64
0
10
0
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
10
0
0
10
0
0
0
0
10
19
0
0
10
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
19
0
0
0
0
% K
% Leu:
10
0
10
28
10
0
0
0
10
0
0
55
10
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
10
55
10
0
% M
% Asn:
10
0
0
0
0
19
19
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
10
0
0
0
10
0
0
0
10
0
0
55
% P
% Gln:
0
0
10
0
0
10
10
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
10
46
0
0
0
10
% R
% Ser:
0
0
0
0
0
55
0
0
0
0
0
0
0
10
19
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
10
10
0
0
% T
% Val:
0
0
10
0
19
0
55
0
0
10
10
10
0
55
0
% V
% Trp:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
55
0
0
0
10
55
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _