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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS1
All Species:
25.15
Human Site:
Y262
Identified Species:
55.33
UniProt:
Q96LJ7
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96LJ7
NP_001129522.1
313
33909
Y262
S
C
D
L
A
R
R
Y
G
L
R
D
V
D
G
Chimpanzee
Pan troglodytes
XP_001169595
313
33804
Y262
S
C
D
L
A
R
R
Y
G
L
R
D
V
D
G
Rhesus Macaque
Macaca mulatta
XP_001113707
313
34036
Y262
S
C
D
L
A
R
R
Y
G
L
R
D
V
D
G
Dog
Lupus familis
XP_537393
296
32202
Y245
S
C
D
L
A
R
R
Y
S
L
Q
D
V
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99L04
313
33987
Y262
S
C
D
L
A
R
R
Y
G
L
K
D
I
D
G
Rat
Rattus norvegicus
Q4V8F9
524
58325
V474
P
S
D
R
A
D
V
V
M
S
M
A
T
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520394
294
31581
H242
H
M
N
Q
A
G
R
H
R
S
T
A
W
F
A
Chicken
Gallus gallus
Q8JIS3
246
26149
P196
G
R
I
N
W
S
D
P
Q
K
S
A
A
M
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002205
310
33871
Y259
T
C
E
L
A
R
R
Y
G
F
K
D
V
D
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21929
251
27201
P201
G
R
D
N
W
S
D
P
D
K
K
K
K
M
L
Sea Urchin
Strong. purpuratus
XP_797581
322
34924
Y272
T
M
E
L
A
E
E
Y
G
F
T
D
V
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.6
96.4
77.9
N.A.
82.7
20.2
N.A.
38.6
23.9
N.A.
58.4
N.A.
N.A.
N.A.
22
50.6
Protein Similarity:
100
93.9
98
84.9
N.A.
91
32.2
N.A.
51.4
40.8
N.A.
77
N.A.
N.A.
N.A.
38
69.8
P-Site Identity:
100
100
100
86.6
N.A.
86.6
13.3
N.A.
13.3
0
N.A.
73.3
N.A.
N.A.
N.A.
6.6
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
100
20
N.A.
26.6
0
N.A.
93.3
N.A.
N.A.
N.A.
13.3
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
82
0
0
0
0
0
0
28
10
0
10
% A
% Cys:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
64
0
0
10
19
0
10
0
0
64
0
64
10
% D
% Glu:
0
0
19
0
0
10
10
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
19
0
0
0
10
0
% F
% Gly:
19
0
0
0
0
10
0
0
55
0
0
0
0
0
64
% G
% His:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
19
28
10
10
0
0
% K
% Leu:
0
0
0
64
0
0
0
0
0
46
0
0
0
0
10
% L
% Met:
0
19
0
0
0
0
0
0
10
0
10
0
0
19
0
% M
% Asn:
0
0
10
19
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
10
0
10
0
0
0
0
% Q
% Arg:
0
19
0
10
0
55
64
0
10
0
28
0
0
0
0
% R
% Ser:
46
10
0
0
0
19
0
0
10
19
10
0
0
0
0
% S
% Thr:
19
0
0
0
0
0
0
0
0
0
19
0
10
0
0
% T
% Val:
0
0
0
0
0
0
10
10
0
0
0
0
55
0
0
% V
% Trp:
0
0
0
0
19
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _