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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE2E2
All Species:
45.45
Human Site:
Y181
Identified Species:
71.43
UniProt:
Q96LR5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96LR5
NP_689866.1
201
22255
Y181
V
G
S
I
A
T
Q
Y
M
T
N
R
A
E
H
Chimpanzee
Pan troglodytes
XP_001173077
355
37792
Y335
V
G
S
I
A
T
Q
Y
M
T
N
R
A
E
H
Rhesus Macaque
Macaca mulatta
XP_001100742
207
22864
Y187
V
G
S
I
A
T
Q
Y
L
T
N
R
A
E
H
Dog
Lupus familis
XP_852428
205
22637
Y180
V
G
S
I
A
T
Q
Y
I
T
N
R
A
E
H
Cat
Felis silvestris
Mouse
Mus musculus
Q91W82
201
22223
Y181
V
G
S
I
A
T
Q
Y
M
T
N
R
A
E
H
Rat
Rattus norvegicus
P62839
147
16717
K128
P
E
I
A
R
I
Y
K
T
D
R
E
K
Y
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509467
201
22210
Y181
V
G
S
I
A
T
Q
Y
M
T
N
R
A
E
H
Chicken
Gallus gallus
XP_001235055
201
22025
Y181
V
G
S
I
A
T
Q
Y
M
T
N
R
A
E
H
Frog
Xenopus laevis
NP_001088106
201
22151
Y181
V
G
S
I
A
T
Q
Y
M
T
N
R
A
E
H
Zebra Danio
Brachydanio rerio
NP_001003494
201
22181
Y181
V
G
S
I
A
T
Q
Y
L
T
N
R
T
E
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P52485
232
24417
Y212
V
G
S
I
A
T
Q
Y
L
Q
N
R
E
E
H
Honey Bee
Apis mellifera
XP_395589
288
32000
Y268
V
G
S
I
A
T
Q
Y
L
Q
N
R
E
E
H
Nematode Worm
Caenorhab. elegans
P35129
147
16687
K128
P
E
I
A
R
I
Y
K
T
D
R
E
R
Y
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P35134
148
16533
T129
E
I
A
H
M
Y
K
T
D
R
S
K
Y
E
S
Baker's Yeast
Sacchar. cerevisiae
P15732
148
16262
K129
P
E
I
A
Q
I
Y
K
T
D
K
A
K
Y
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.7
85.9
94.6
N.A.
99.5
47.7
N.A.
98
92
96
89.5
N.A.
67.6
55.5
48.2
N.A.
Protein Similarity:
100
52.9
90.8
96
N.A.
100
57.7
N.A.
98.5
94.5
97.5
94
N.A.
71.9
61.1
58.2
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
100
0
N.A.
100
100
100
86.6
N.A.
80
80
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
100
100
100
93.3
N.A.
86.6
86.6
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.2
48.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.7
58.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
20
74
0
0
0
0
0
0
7
54
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
20
0
0
0
0
0
% D
% Glu:
7
20
0
0
0
0
0
0
0
0
0
14
14
80
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
74
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
74
% H
% Ile:
0
7
20
74
0
20
0
0
7
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
7
20
0
0
7
7
14
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
27
0
0
0
0
0
0
% L
% Met:
0
0
0
0
7
0
0
0
40
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
74
0
0
0
14
% N
% Pro:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
74
0
0
14
0
0
0
0
0
% Q
% Arg:
0
0
0
0
14
0
0
0
0
7
14
74
7
0
0
% R
% Ser:
0
0
74
0
0
0
0
0
0
0
7
0
0
0
7
% S
% Thr:
0
0
0
0
0
74
0
7
20
60
0
0
7
0
0
% T
% Val:
74
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
20
74
0
0
0
0
7
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _