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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf72
All Species:
26.67
Human Site:
T204
Identified Species:
65.19
UniProt:
Q96LT7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96LT7
NP_060795.1
481
54328
T204
E
E
I
D
I
A
D
T
V
L
N
D
D
D
I
Chimpanzee
Pan troglodytes
XP_001154920
481
54326
T204
E
E
I
D
I
A
D
T
V
L
N
D
D
D
I
Rhesus Macaque
Macaca mulatta
XP_001104667
481
54284
T204
E
E
I
D
I
A
D
T
V
L
N
D
D
D
I
Dog
Lupus familis
XP_852187
481
54271
T204
E
E
I
D
I
A
D
T
V
L
N
D
D
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6DFW0
420
47296
E152
W
M
H
K
E
R
Q
E
N
V
Q
K
I
V
L
Rat
Rattus norvegicus
Q66HC3
481
54287
T204
E
D
L
D
I
A
D
T
V
L
N
D
D
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505281
481
54381
T204
A
E
I
D
I
R
D
T
V
L
S
D
D
D
I
Chicken
Gallus gallus
XP_424945
481
54509
T204
E
E
I
D
I
S
D
T
V
L
N
D
D
D
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_991166
462
51892
D194
L
N
D
D
D
I
G
D
S
C
H
E
D
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798968
453
51801
M185
G
L
L
F
M
A
P
M
P
T
Q
V
N
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.5
98.5
N.A.
85.4
97.7
N.A.
94.8
93.5
N.A.
72.9
N.A.
N.A.
N.A.
N.A.
34.3
Protein Similarity:
100
99.7
99.7
99.3
N.A.
87.1
99.7
N.A.
98.3
98.3
N.A.
85.8
N.A.
N.A.
N.A.
N.A.
53.4
P-Site Identity:
100
100
100
100
N.A.
0
86.6
N.A.
80
93.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
13.3
100
N.A.
86.6
100
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
60
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
10
10
80
10
0
70
10
0
0
0
70
80
70
0
% D
% Glu:
60
60
0
0
10
0
0
10
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
60
0
70
10
0
0
0
0
0
0
10
0
70
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
10
10
20
0
0
0
0
0
0
70
0
0
0
10
20
% L
% Met:
0
10
0
0
10
0
0
10
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
10
0
60
0
10
0
10
% N
% Pro:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
20
0
0
0
0
% Q
% Arg:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
10
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
70
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
70
10
0
10
0
10
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _