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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C9orf72
All Species:
28.18
Human Site:
T420
Identified Species:
68.89
UniProt:
Q96LT7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96LT7
NP_060795.1
481
54328
T420
I
K
Y
I
E
D
D
T
Q
K
G
K
K
P
F
Chimpanzee
Pan troglodytes
XP_001154920
481
54326
T420
I
K
Y
I
E
D
D
T
Q
K
G
K
K
P
F
Rhesus Macaque
Macaca mulatta
XP_001104667
481
54284
T420
I
K
Y
I
E
D
D
T
Q
K
G
K
K
P
F
Dog
Lupus familis
XP_852187
481
54271
T420
I
K
Y
I
E
D
D
T
Q
K
G
K
K
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6DFW0
420
47296
I366
S
F
T
P
D
L
N
I
F
Q
D
V
L
H
R
Rat
Rattus norvegicus
Q66HC3
481
54287
T420
I
K
Y
I
E
D
D
T
Q
K
G
K
K
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505281
481
54381
T420
I
K
Y
I
E
D
D
T
Q
K
G
K
R
P
F
Chicken
Gallus gallus
XP_424945
481
54509
T420
I
K
Y
I
E
D
D
T
Q
K
G
K
K
P
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_991166
462
51892
F408
T
Q
K
G
K
K
P
F
R
S
L
R
N
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798968
453
51801
S399
T
D
R
G
T
H
P
S
K
V
T
L
R
K
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.5
98.5
N.A.
85.4
97.7
N.A.
94.8
93.5
N.A.
72.9
N.A.
N.A.
N.A.
N.A.
34.3
Protein Similarity:
100
99.7
99.7
99.3
N.A.
87.1
99.7
N.A.
98.3
98.3
N.A.
85.8
N.A.
N.A.
N.A.
N.A.
53.4
P-Site Identity:
100
100
100
100
N.A.
0
100
N.A.
93.3
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
20
100
N.A.
100
100
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
70
70
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
70
% F
% Gly:
0
0
0
20
0
0
0
0
0
0
70
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% H
% Ile:
70
0
0
70
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
70
10
0
10
10
0
0
10
70
0
70
60
10
10
% K
% Leu:
0
0
0
0
0
10
0
0
0
0
10
10
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
10
0
0
20
0
0
0
0
0
0
70
0
% P
% Gln:
0
10
0
0
0
0
0
0
70
10
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
0
0
0
10
0
0
10
20
0
10
% R
% Ser:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% S
% Thr:
20
0
10
0
10
0
0
70
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _