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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYLS1
All Species:
24.55
Human Site:
S120
Identified Species:
60
UniProt:
Q96M11
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96M11
NP_001128265.1
299
34359
S120
S
I
I
S
E
S
E
S
G
T
E
N
D
Q
D
Chimpanzee
Pan troglodytes
XP_508880
298
34223
S119
S
I
I
S
E
S
E
S
G
T
E
N
D
Q
D
Rhesus Macaque
Macaca mulatta
XP_001111926
299
34413
S120
S
I
I
S
E
S
E
S
G
T
E
N
D
Q
G
Dog
Lupus familis
XP_852042
300
34499
S121
S
I
I
S
E
S
E
S
G
T
E
S
D
M
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXX0
307
35123
S134
S
V
I
S
E
C
E
S
G
T
E
S
D
L
G
Rat
Rattus norvegicus
XP_001056376
313
35709
S134
S
I
I
S
E
S
E
S
G
T
E
S
D
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519328
236
25944
L89
V
Y
V
P
N
T
Y
L
V
P
T
E
K
K
R
Chicken
Gallus gallus
XP_001231543
277
30879
T101
S
V
T
S
L
L
E
T
T
A
T
W
N
L
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504840
274
32164
S112
S
D
F
D
D
E
S
S
N
E
Y
P
E
R
N
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SUG3
353
39612
A185
P
L
V
A
D
G
S
A
K
S
H
E
L
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.3
88
N.A.
78.1
78.9
N.A.
20.7
38.1
N.A.
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
100
99.6
98.3
93
N.A.
82.4
84.3
N.A.
35.4
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
66.6
86.6
N.A.
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
80
93.3
N.A.
20
40
N.A.
N.A.
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
20
0
0
0
0
0
0
0
60
0
40
% D
% Glu:
0
0
0
0
60
10
70
0
0
10
60
20
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
60
0
0
0
0
0
20
% G
% His:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
50
60
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% K
% Leu:
0
10
0
0
10
10
0
10
0
0
0
0
10
30
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
10
0
0
0
10
0
0
30
10
0
10
% N
% Pro:
10
0
0
10
0
0
0
0
0
10
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% R
% Ser:
80
0
0
70
0
50
20
70
0
10
0
30
0
10
0
% S
% Thr:
0
0
10
0
0
10
0
10
10
60
20
0
0
0
10
% T
% Val:
10
20
20
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
10
0
0
0
0
10
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _