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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYLS1
All Species:
16.36
Human Site:
S146
Identified Species:
40
UniProt:
Q96M11
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96M11
NP_001128265.1
299
34359
S146
Q
F
Q
E
D
K
E
S
S
F
D
V
S
Q
K
Chimpanzee
Pan troglodytes
XP_508880
298
34223
S145
Q
F
Q
E
D
K
E
S
S
F
D
V
S
Q
K
Rhesus Macaque
Macaca mulatta
XP_001111926
299
34413
S146
Q
F
Q
E
D
K
E
S
S
F
D
I
S
Q
K
Dog
Lupus familis
XP_852042
300
34499
S147
Q
F
Q
E
D
M
D
S
P
D
D
I
P
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXX0
307
35123
P161
F
Q
E
G
T
E
S
P
V
V
T
S
Q
K
F
Rat
Rattus norvegicus
XP_001056376
313
35709
S160
Q
F
Q
E
G
T
A
S
P
V
D
T
S
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519328
236
25944
P106
L
R
W
G
S
E
D
P
A
R
R
R
L
R
L
Chicken
Gallus gallus
XP_001231543
277
30879
E128
S
L
S
E
G
E
I
E
M
S
S
S
F
F
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504840
274
32164
T142
T
C
N
G
A
T
E
T
L
K
S
I
S
L
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SUG3
353
39612
H214
V
L
Q
E
F
V
N
H
G
G
V
L
F
K
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.3
88
N.A.
78.1
78.9
N.A.
20.7
38.1
N.A.
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
100
99.6
98.3
93
N.A.
82.4
84.3
N.A.
35.4
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
0
60
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
20
60
N.A.
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
10
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
40
0
20
0
0
10
50
0
0
0
10
% D
% Glu:
0
0
10
70
0
30
40
10
0
0
0
0
0
0
0
% E
% Phe:
10
50
0
0
10
0
0
0
0
30
0
0
20
10
10
% F
% Gly:
0
0
0
30
20
0
0
0
10
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
30
0
0
0
% I
% Lys:
0
0
0
0
0
30
0
0
0
10
0
0
0
20
50
% K
% Leu:
10
20
0
0
0
0
0
0
10
0
0
10
10
10
10
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
20
20
0
0
0
10
0
0
% P
% Gln:
50
10
60
0
0
0
0
0
0
0
0
0
10
50
10
% Q
% Arg:
0
10
0
0
0
0
0
0
0
10
10
10
0
10
0
% R
% Ser:
10
0
10
0
10
0
10
50
30
10
20
20
50
0
0
% S
% Thr:
10
0
0
0
10
20
0
10
0
0
10
10
0
0
0
% T
% Val:
10
0
0
0
0
10
0
0
10
20
10
20
0
0
10
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _