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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYLS1
All Species:
20.61
Human Site:
S171
Identified Species:
50.37
UniProt:
Q96M11
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96M11
NP_001128265.1
299
34359
S171
S
Q
D
Q
L
I
C
S
L
Q
R
E
G
M
G
Chimpanzee
Pan troglodytes
XP_508880
298
34223
S170
S
Q
D
Q
L
I
C
S
L
Q
R
E
G
M
G
Rhesus Macaque
Macaca mulatta
XP_001111926
299
34413
S171
S
Q
D
Q
L
I
C
S
L
Q
R
E
G
M
G
Dog
Lupus familis
XP_852042
300
34499
Y172
S
Q
D
Q
L
I
C
Y
L
Q
R
E
G
M
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXX0
307
35123
Y186
Q
E
D
Q
L
I
C
Y
L
Q
R
E
E
M
D
Rat
Rattus norvegicus
XP_001056376
313
35709
Y185
S
Q
D
Q
L
I
C
Y
L
Q
R
E
E
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519328
236
25944
E131
R
R
Y
P
G
L
G
E
G
G
E
L
G
R
G
Chicken
Gallus gallus
XP_001231543
277
30879
L153
A
Q
C
D
P
P
F
L
L
R
V
V
Q
S
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504840
274
32164
E167
D
D
E
E
N
I
A
E
S
V
S
V
G
L
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SUG3
353
39612
V239
R
R
F
S
L
P
D
V
S
R
R
E
L
P
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.3
88
N.A.
78.1
78.9
N.A.
20.7
38.1
N.A.
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
100
99.6
98.3
93
N.A.
82.4
84.3
N.A.
35.4
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
66.6
86.6
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
86.6
N.A.
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
60
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
60
10
0
0
10
0
0
0
0
0
0
0
10
% D
% Glu:
0
10
10
10
0
0
0
20
0
0
10
70
20
0
0
% E
% Phe:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
10
10
0
0
60
0
60
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
0
0
0
70
10
0
10
70
0
0
10
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
20
0
0
0
0
0
0
0
10
0
% P
% Gln:
10
60
0
60
0
0
0
0
0
60
0
0
10
0
10
% Q
% Arg:
20
20
0
0
0
0
0
0
0
20
70
0
0
10
0
% R
% Ser:
50
0
0
10
0
0
0
30
20
0
10
0
0
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
10
0
10
10
20
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
30
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _