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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYLS1
All Species:
19.39
Human Site:
S253
Identified Species:
47.41
UniProt:
Q96M11
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96M11
NP_001128265.1
299
34359
S253
L
C
R
A
E
P
Q
S
K
P
Q
H
I
Y
V
Chimpanzee
Pan troglodytes
XP_508880
298
34223
S252
L
C
R
A
E
P
Q
S
K
P
Q
H
I
Y
V
Rhesus Macaque
Macaca mulatta
XP_001111926
299
34413
S253
L
C
R
A
E
P
Q
S
K
P
Q
H
I
Y
V
Dog
Lupus familis
XP_852042
300
34499
A254
L
S
R
P
E
P
Q
A
K
P
Q
H
I
Y
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXX0
307
35123
S268
L
S
R
T
E
P
P
S
K
P
Q
H
V
Y
V
Rat
Rattus norvegicus
XP_001056376
313
35709
S267
L
S
R
P
E
P
Q
S
K
P
Q
H
L
Y
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519328
236
25944
R200
P
N
K
E
S
F
T
R
Q
R
S
P
V
F
L
Chicken
Gallus gallus
XP_001231543
277
30879
S235
L
T
Q
H
S
H
P
S
K
P
Q
H
T
Y
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504840
274
32164
W238
M
R
R
L
S
L
R
W
K
V
R
E
F
M
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SUG3
353
39612
R308
I
I
R
E
H
G
T
R
D
R
F
Y
V
I
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.3
88
N.A.
78.1
78.9
N.A.
20.7
38.1
N.A.
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
100
99.6
98.3
93
N.A.
82.4
84.3
N.A.
35.4
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
100
100
100
80
N.A.
73.3
80
N.A.
0
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
80
86.6
N.A.
33.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
30
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% D
% Glu:
0
0
0
20
60
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
10
0
10
10
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
10
10
0
0
0
0
0
70
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
0
0
0
40
10
10
% I
% Lys:
0
0
10
0
0
0
0
0
80
0
0
0
0
0
0
% K
% Leu:
70
0
0
10
0
10
0
0
0
0
0
0
10
0
20
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
20
0
60
20
0
0
70
0
10
0
0
0
% P
% Gln:
0
0
10
0
0
0
50
0
10
0
70
0
0
0
0
% Q
% Arg:
0
10
80
0
0
0
10
20
0
20
10
0
0
0
0
% R
% Ser:
0
30
0
0
30
0
0
60
0
0
10
0
0
0
0
% S
% Thr:
0
10
0
10
0
0
20
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
30
0
60
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
70
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _