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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYLS1
All Species:
14.24
Human Site:
S45
Identified Species:
34.81
UniProt:
Q96M11
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96M11
NP_001128265.1
299
34359
S45
D
V
R
R
E
A
Q
S
I
Q
Y
D
P
Y
S
Chimpanzee
Pan troglodytes
XP_508880
298
34223
S45
D
V
R
R
E
A
Q
S
I
Q
Y
D
P
Y
S
Rhesus Macaque
Macaca mulatta
XP_001111926
299
34413
S45
D
V
R
R
E
A
Q
S
I
Q
Y
D
P
Y
S
Dog
Lupus familis
XP_852042
300
34499
S46
D
V
R
R
D
A
R
S
I
Q
Y
D
P
Y
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXX0
307
35123
A59
D
S
R
R
E
A
Q
A
G
Q
Y
D
P
Y
S
Rat
Rattus norvegicus
XP_001056376
313
35709
A59
D
S
R
R
E
V
Q
A
G
Q
Y
D
P
Y
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519328
236
25944
S23
Q
R
G
A
R
P
P
S
Y
D
P
Y
S
K
A
Chicken
Gallus gallus
XP_001231543
277
30879
L34
H
G
A
E
G
A
P
L
C
C
S
A
Y
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504840
274
32164
C43
N
L
L
D
R
E
L
C
L
S
D
A
D
E
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SUG3
353
39612
D111
E
F
R
L
A
H
P
D
V
T
V
L
D
P
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.3
88
N.A.
78.1
78.9
N.A.
20.7
38.1
N.A.
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
100
99.6
98.3
93
N.A.
82.4
84.3
N.A.
35.4
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
73.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
86.6
80
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
10
60
0
20
0
0
0
20
0
10
20
% A
% Cys:
0
0
0
0
0
0
0
10
10
10
0
0
0
0
0
% C
% Asp:
60
0
0
10
10
0
0
10
0
10
10
60
20
0
10
% D
% Glu:
10
0
0
10
50
10
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
10
0
0
0
20
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
40
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
10
10
10
0
0
10
10
10
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
10
30
0
0
0
10
0
60
10
10
% P
% Gln:
10
0
0
0
0
0
50
0
0
60
0
0
0
0
0
% Q
% Arg:
0
10
70
60
20
0
10
0
0
0
0
0
0
0
0
% R
% Ser:
0
20
0
0
0
0
0
50
0
10
10
0
10
0
60
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% T
% Val:
0
40
0
0
0
10
0
0
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
60
10
10
60
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _