KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYLS1
All Species:
21.82
Human Site:
S55
Identified Species:
53.33
UniProt:
Q96M11
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96M11
NP_001128265.1
299
34359
S55
Y
D
P
Y
S
K
A
S
V
A
P
G
K
R
P
Chimpanzee
Pan troglodytes
XP_508880
298
34223
S55
Y
D
P
Y
S
K
A
S
V
A
P
G
K
R
P
Rhesus Macaque
Macaca mulatta
XP_001111926
299
34413
S55
Y
D
P
Y
S
K
A
S
I
A
P
G
K
R
P
Dog
Lupus familis
XP_852042
300
34499
S56
Y
D
P
Y
S
K
A
S
V
T
P
G
K
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXX0
307
35123
S69
Y
D
P
Y
S
K
A
S
V
T
P
G
K
R
P
Rat
Rattus norvegicus
XP_001056376
313
35709
S69
Y
D
P
Y
S
K
A
S
I
T
P
G
K
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519328
236
25944
T33
P
Y
S
K
A
S
V
T
P
G
G
W
P
L
L
Chicken
Gallus gallus
XP_001231543
277
30879
A44
S
A
Y
A
A
P
T
A
L
Q
A
A
R
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504840
274
32164
N53
D
A
D
E
D
V
M
N
E
S
L
F
A
S
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SUG3
353
39612
I121
V
L
D
P
P
D
A
I
L
H
L
R
N
R
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.3
88
N.A.
78.1
78.9
N.A.
20.7
38.1
N.A.
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
100
99.6
98.3
93
N.A.
82.4
84.3
N.A.
35.4
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
80
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
86.6
N.A.
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
10
20
0
70
10
0
30
10
10
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
60
20
0
10
10
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
10
60
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
20
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
60
0
0
0
0
0
0
60
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
20
0
20
0
0
10
30
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
10
0
60
10
10
10
0
0
10
0
60
0
10
0
50
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
10
70
0
% R
% Ser:
10
0
10
0
60
10
0
60
0
10
0
0
0
20
0
% S
% Thr:
0
0
0
0
0
0
10
10
0
30
0
0
0
0
0
% T
% Val:
10
0
0
0
0
10
10
0
40
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
60
10
10
60
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _