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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYLS1
All Species:
20.3
Human Site:
S79
Identified Species:
49.63
UniProt:
Q96M11
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96M11
NP_001128265.1
299
34359
S79
H
V
E
S
N
V
P
S
E
T
V
S
E
A
S
Chimpanzee
Pan troglodytes
XP_508880
298
34223
S79
H
V
E
S
N
V
P
S
E
T
V
S
E
A
S
Rhesus Macaque
Macaca mulatta
XP_001111926
299
34413
S79
H
V
E
S
N
V
T
S
E
T
V
S
E
A
S
Dog
Lupus familis
XP_852042
300
34499
S80
H
V
E
S
N
A
T
S
V
T
V
S
E
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXX0
307
35123
S93
H
T
A
S
R
V
T
S
S
T
V
S
E
T
S
Rat
Rattus norvegicus
XP_001056376
313
35709
S93
Y
T
G
S
H
V
T
S
S
T
V
S
E
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519328
236
25944
P57
E
G
A
G
P
P
E
P
A
P
Q
L
R
W
G
Chicken
Gallus gallus
XP_001231543
277
30879
K68
S
A
A
P
W
C
P
K
G
S
R
R
Q
V
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_504840
274
32164
T77
R
Q
E
R
N
F
P
T
E
N
L
N
I
Q
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SUG3
353
39612
R145
N
L
S
D
S
N
G
R
V
G
V
P
K
Q
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.3
88
N.A.
78.1
78.9
N.A.
20.7
38.1
N.A.
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
100
99.6
98.3
93
N.A.
82.4
84.3
N.A.
35.4
51.1
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
60
53.3
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
100
100
93.3
73.3
N.A.
60
66.6
N.A.
0
20
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
30
0
0
10
0
0
10
0
0
0
0
30
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
50
0
0
0
10
0
40
0
0
0
60
0
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
10
0
0
10
0
10
10
0
0
0
0
10
% G
% His:
50
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
0
10
10
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
0
0
50
10
0
0
0
10
0
10
0
0
0
% N
% Pro:
0
0
0
10
10
10
40
10
0
10
0
10
0
10
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
10
0
10
20
0
% Q
% Arg:
10
0
0
10
10
0
0
10
0
0
10
10
10
0
0
% R
% Ser:
10
0
10
60
10
0
0
60
20
10
0
60
0
0
70
% S
% Thr:
0
20
0
0
0
0
40
10
0
60
0
0
0
20
0
% T
% Val:
0
40
0
0
0
50
0
0
20
0
70
0
0
10
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _