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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HYLS1 All Species: 13.03
Human Site: T210 Identified Species: 31.85
UniProt: Q96M11 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96M11 NP_001128265.1 299 34359 T210 L S R N R G K T D R V A R Y F
Chimpanzee Pan troglodytes XP_508880 298 34223 T209 L S R N R G K T D R V A R Y F
Rhesus Macaque Macaca mulatta XP_001111926 299 34413 T210 L S R N R G K T D R V A R Y F
Dog Lupus familis XP_852042 300 34499 V211 L S R N R G K V D R V A R Y F
Cat Felis silvestris
Mouse Mus musculus Q9CXX0 307 35123 I225 L S R N R G K I D R V A R Y F
Rat Rattus norvegicus XP_001056376 313 35709 I224 L S R N R G K I D R V A R Y F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519328 236 25944 V170 R A F T L L R V G G A R R F Q
Chicken Gallus gallus XP_001231543 277 30879 S192 L R Q N R S K S D R V A K Y F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_504840 274 32164 P206 S L E P G R A P K K Y D P V T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SUG3 353 39612 R278 S I A E L P P R P L L E R L A
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 97.3 88 N.A. 78.1 78.9 N.A. 20.7 38.1 N.A. N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: 100 99.6 98.3 93 N.A. 82.4 84.3 N.A. 35.4 51.1 N.A. N.A. N.A. N.A. N.A. 35.4 N.A.
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 6.6 66.6 N.A. N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. 26.6 86.6 N.A. N.A. N.A. N.A. N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 0 10 0 0 0 10 70 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 70 0 0 10 0 0 0 % D
% Glu: 0 0 10 10 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 70 % F
% Gly: 0 0 0 0 10 60 0 0 10 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 20 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 70 0 10 10 0 0 10 0 0 % K
% Leu: 70 10 0 0 20 10 0 0 0 10 10 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 70 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 10 10 10 10 0 0 0 10 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 10 % Q
% Arg: 10 10 60 0 70 10 10 10 0 70 0 10 80 0 0 % R
% Ser: 20 60 0 0 0 10 0 10 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 10 0 0 0 30 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 20 0 0 70 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 70 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _