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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRGUK All Species: 5.76
Human Site: S15 Identified Species: 14.07
UniProt: Q96M69 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96M69 NP_653249.1 825 93618 S15 L L R T R A A S L L R G L G R
Chimpanzee Pan troglodytes XP_519392 825 93474 S15 L L R T R A A S L L R G L G R
Rhesus Macaque Macaca mulatta XP_001100217 826 93344 L16 V R T R A S S L L R G L G R S
Dog Lupus familis XP_532416 825 93664 S15 P P G P R P S S L Q S R A R A
Cat Felis silvestris
Mouse Mus musculus Q9D5S7 820 93171 R15 P S R W K G T R F R R G L G A
Rat Rattus norvegicus NP_001100059 820 93260 F16 S R W K G T R F Q R S L G A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511590 1485 165149 Q16 V V S D P G W Q R I S E D W K
Chicken Gallus gallus XP_414995 547 62520
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116719 730 80821
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786893 782 86745 F15 S R P Q T V S F S D L T E R T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 93.2 77.3 N.A. 73.4 73.5 N.A. 37.1 43.3 N.A. 41.9 N.A. N.A. N.A. N.A. 34.6
Protein Similarity: 100 99.6 95.5 84.8 N.A. 82.5 82.3 N.A. 44.7 53.5 N.A. 55.5 N.A. N.A. N.A. N.A. 55.1
P-Site Identity: 100 100 6.6 20 N.A. 33.3 0 N.A. 0 0 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 26.6 26.6 N.A. 40 0 N.A. 26.6 0 N.A. 0 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 20 20 0 0 0 0 0 10 10 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 10 0 0 10 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 20 10 0 0 0 0 0 0 % F
% Gly: 0 0 10 0 10 20 0 0 0 0 10 30 20 30 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 10 10 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 20 20 0 0 0 0 0 10 40 20 10 20 30 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 20 10 10 10 10 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 10 0 0 0 10 10 10 0 0 0 0 0 % Q
% Arg: 0 30 30 10 30 0 10 10 10 30 30 10 0 30 20 % R
% Ser: 20 10 10 0 0 10 30 30 10 0 30 0 0 0 20 % S
% Thr: 0 0 10 20 10 10 10 0 0 0 0 10 0 0 10 % T
% Val: 20 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 10 10 0 0 10 0 0 0 0 0 0 10 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _