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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LRGUK All Species: 13.64
Human Site: S609 Identified Species: 33.33
UniProt: Q96M69 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96M69 NP_653249.1 825 93618 S609 L T E E P A K S L A T T A D V
Chimpanzee Pan troglodytes XP_519392 825 93474 S609 L T E E P A K S L A T T A D V
Rhesus Macaque Macaca mulatta XP_001100217 826 93344 S610 L T K E P A K S L A T T A D G
Dog Lupus familis XP_532416 825 93664 N609 L S E E T S K N L A P T A D I
Cat Felis silvestris
Mouse Mus musculus Q9D5S7 820 93171 T609 L T E T A A K T L A P T A D T
Rat Rattus norvegicus NP_001100059 820 93260 G608 L T E T A K K G L A P T A D T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511590 1485 165149 L597 L A E N D K D L T L S E N K A
Chicken Gallus gallus XP_414995 547 62520 V339 Q Y D P P P E V V A A K D H M
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116719 730 80821 T522 I T P D N T S T N T T G E L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786893 782 86745 E566 L E V P D S P E P S S Q E Q D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 93.2 77.3 N.A. 73.4 73.5 N.A. 37.1 43.3 N.A. 41.9 N.A. N.A. N.A. N.A. 34.6
Protein Similarity: 100 99.6 95.5 84.8 N.A. 82.5 82.3 N.A. 44.7 53.5 N.A. 55.5 N.A. N.A. N.A. N.A. 55.1
P-Site Identity: 100 100 86.6 60 N.A. 66.6 60 N.A. 13.3 13.3 N.A. 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 93.3 86.6 N.A. 73.3 60 N.A. 20 40 N.A. 33.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 20 40 0 0 0 70 10 0 60 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 20 0 10 0 0 0 0 0 10 60 10 % D
% Glu: 0 10 60 40 0 0 10 10 0 0 0 10 20 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % I
% Lys: 0 0 10 0 0 20 60 0 0 0 0 10 0 10 0 % K
% Leu: 80 0 0 0 0 0 0 10 60 10 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 10 10 0 0 10 10 0 0 0 10 0 0 % N
% Pro: 0 0 10 20 40 10 10 0 10 0 30 0 0 0 10 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 0 0 20 10 30 0 10 20 0 0 0 0 % S
% Thr: 0 60 0 20 10 10 0 20 10 10 40 60 0 0 20 % T
% Val: 0 0 10 0 0 0 0 10 10 0 0 0 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _