KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRGUK
All Species:
16.97
Human Site:
T618
Identified Species:
41.48
UniProt:
Q96M69
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96M69
NP_653249.1
825
93618
T618
A
T
T
A
D
V
K
T
S
H
L
K
P
E
A
Chimpanzee
Pan troglodytes
XP_519392
825
93474
T618
A
T
T
A
D
V
K
T
S
H
L
K
P
E
A
Rhesus Macaque
Macaca mulatta
XP_001100217
826
93344
T619
A
T
T
A
D
G
K
T
S
H
L
K
S
E
V
Dog
Lupus familis
XP_532416
825
93664
I618
A
P
T
A
D
I
K
I
P
Q
L
K
S
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5S7
820
93171
T618
A
P
T
A
D
T
K
T
S
Y
L
K
C
E
D
Rat
Rattus norvegicus
NP_001100059
820
93260
T617
A
P
T
A
D
T
K
T
S
Y
V
K
S
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511590
1485
165149
T606
L
S
E
N
K
A
T
T
I
A
A
N
N
R
K
Chicken
Gallus gallus
XP_414995
547
62520
Q348
A
A
K
D
H
M
T
Q
L
M
Y
S
M
L
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116719
730
80821
A531
T
T
G
E
L
P
A
A
S
A
T
E
S
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786893
782
86745
S575
S
S
Q
E
Q
D
S
S
S
I
Y
S
P
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93.2
77.3
N.A.
73.4
73.5
N.A.
37.1
43.3
N.A.
41.9
N.A.
N.A.
N.A.
N.A.
34.6
Protein Similarity:
100
99.6
95.5
84.8
N.A.
82.5
82.3
N.A.
44.7
53.5
N.A.
55.5
N.A.
N.A.
N.A.
N.A.
55.1
P-Site Identity:
100
100
80
53.3
N.A.
66.6
60
N.A.
6.6
6.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
80
60
N.A.
73.3
73.3
N.A.
13.3
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
70
10
0
60
0
10
10
10
0
20
10
0
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
0
10
60
10
0
0
0
0
0
0
0
0
30
% D
% Glu:
0
0
10
20
0
0
0
0
0
0
0
10
0
60
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
30
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
10
10
10
0
0
0
0
0
% I
% Lys:
0
0
10
0
10
0
60
0
0
0
0
60
0
0
10
% K
% Leu:
10
0
0
0
10
0
0
0
10
0
50
0
0
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
10
0
0
10
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
10
10
0
0
% N
% Pro:
0
30
0
0
0
10
0
0
10
0
0
0
30
0
0
% P
% Gln:
0
0
10
0
10
0
0
10
0
10
0
0
0
0
20
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
10
20
0
0
0
0
10
10
70
0
0
20
40
10
0
% S
% Thr:
10
40
60
0
0
20
20
60
0
0
10
0
0
10
0
% T
% Val:
0
0
0
0
0
20
0
0
0
0
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
20
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _