KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRGUK
All Species:
11.82
Human Site:
Y646
Identified Species:
28.89
UniProt:
Q96M69
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96M69
NP_653249.1
825
93618
Y646
L
H
S
T
D
R
N
Y
L
I
K
F
W
A
K
Chimpanzee
Pan troglodytes
XP_519392
825
93474
Y646
L
H
S
T
D
R
N
Y
L
V
K
L
W
A
K
Rhesus Macaque
Macaca mulatta
XP_001100217
826
93344
Y647
L
H
S
T
D
R
N
Y
L
V
K
L
W
T
K
Dog
Lupus familis
XP_532416
825
93664
Y646
L
E
S
T
D
R
N
Y
F
V
K
L
W
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5S7
820
93171
K646
T
D
R
N
Y
F
T
K
L
W
A
K
L
S
S
Rat
Rattus norvegicus
NP_001100059
820
93260
K645
T
D
R
N
Y
F
T
K
L
W
A
K
L
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511590
1485
165149
A634
R
R
L
A
K
L
E
A
G
G
S
T
T
E
F
Chicken
Gallus gallus
XP_414995
547
62520
L376
A
P
Y
P
M
L
V
L
V
G
P
L
A
C
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116719
730
80821
R559
Q
A
N
M
T
P
Q
R
T
E
M
A
S
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786893
782
86745
R603
S
F
S
Q
S
T
G
R
Q
Q
G
P
P
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93.2
77.3
N.A.
73.4
73.5
N.A.
37.1
43.3
N.A.
41.9
N.A.
N.A.
N.A.
N.A.
34.6
Protein Similarity:
100
99.6
95.5
84.8
N.A.
82.5
82.3
N.A.
44.7
53.5
N.A.
55.5
N.A.
N.A.
N.A.
N.A.
55.1
P-Site Identity:
100
86.6
80
73.3
N.A.
6.6
6.6
N.A.
0
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
86.6
80
N.A.
13.3
13.3
N.A.
0
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
0
0
0
10
0
0
20
10
10
30
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
20
0
0
40
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
10
0
0
10
0
0
0
10
0
% E
% Phe:
0
10
0
0
0
20
0
0
10
0
0
10
0
0
10
% F
% Gly:
0
0
0
0
0
0
10
0
10
20
10
0
0
10
10
% G
% His:
0
30
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% I
% Lys:
0
0
0
0
10
0
0
20
0
0
40
20
0
0
40
% K
% Leu:
40
0
10
0
0
20
0
10
50
0
0
40
20
0
0
% L
% Met:
0
0
0
10
10
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
10
20
0
0
40
0
0
0
0
0
0
10
0
% N
% Pro:
0
10
0
10
0
10
0
0
0
0
10
10
10
0
0
% P
% Gln:
10
0
0
10
0
0
10
0
10
10
0
0
0
0
0
% Q
% Arg:
10
10
20
0
0
40
0
20
0
0
0
0
0
0
0
% R
% Ser:
10
0
50
0
10
0
0
0
0
0
10
0
10
20
20
% S
% Thr:
20
0
0
40
10
10
20
0
10
0
0
10
10
10
0
% T
% Val:
0
0
0
0
0
0
10
0
10
30
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
20
0
0
40
0
0
% W
% Tyr:
0
0
10
0
20
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _