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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRGUK
All Species:
10.61
Human Site:
Y721
Identified Species:
25.93
UniProt:
Q96M69
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96M69
NP_653249.1
825
93618
Y721
S
F
D
L
C
E
D
Y
F
K
P
P
F
G
P
Chimpanzee
Pan troglodytes
XP_519392
825
93474
Y721
S
F
D
L
C
E
D
Y
F
K
P
P
F
G
P
Rhesus Macaque
Macaca mulatta
XP_001100217
826
93344
Y722
S
F
D
L
C
E
D
Y
F
K
P
P
F
G
P
Dog
Lupus familis
XP_532416
825
93664
F721
F
E
L
S
E
D
Y
F
K
T
L
I
G
P
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5S7
820
93171
L718
T
F
E
L
S
D
D
L
F
K
T
P
S
G
T
Rat
Rattus norvegicus
NP_001100059
820
93260
H717
T
F
E
L
C
E
D
H
V
K
A
P
F
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511590
1485
165149
A1256
H
W
P
T
G
E
Q
A
P
P
K
I
G
L
S
Chicken
Gallus gallus
XP_414995
547
62520
G445
I
V
T
F
K
Y
S
G
Y
Y
Y
G
L
G
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116719
730
80821
S628
A
P
N
L
S
E
D
S
S
S
E
E
S
R
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786893
782
86745
D675
G
I
V
P
R
P
L
D
Q
L
I
N
E
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93.2
77.3
N.A.
73.4
73.5
N.A.
37.1
43.3
N.A.
41.9
N.A.
N.A.
N.A.
N.A.
34.6
Protein Similarity:
100
99.6
95.5
84.8
N.A.
82.5
82.3
N.A.
44.7
53.5
N.A.
55.5
N.A.
N.A.
N.A.
N.A.
55.1
P-Site Identity:
100
100
100
0
N.A.
46.6
66.6
N.A.
6.6
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
66.6
86.6
N.A.
13.3
13.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
40
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
30
0
0
20
60
10
0
0
0
0
0
0
0
% D
% Glu:
0
10
20
0
10
60
0
0
0
0
10
10
10
0
0
% E
% Phe:
10
50
0
10
0
0
0
10
40
0
0
0
40
0
0
% F
% Gly:
10
0
0
0
10
0
0
10
0
0
0
10
20
60
0
% G
% His:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
0
0
0
0
0
0
10
20
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
10
50
10
0
0
0
0
% K
% Leu:
0
0
10
60
0
0
10
10
0
10
10
0
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
0
10
10
10
0
10
0
0
10
10
30
50
0
20
50
% P
% Gln:
0
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% R
% Ser:
30
0
0
10
20
0
10
10
10
10
0
0
20
0
10
% S
% Thr:
20
0
10
10
0
0
0
0
0
10
10
0
0
0
10
% T
% Val:
0
10
10
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
10
30
10
10
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _