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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIAT1
All Species:
25.15
Human Site:
S236
Identified Species:
46.11
UniProt:
Q96MC6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MC6
NP_149044.2
490
53027
S236
E
Q
A
D
P
F
A
S
L
K
K
V
G
Q
D
Chimpanzee
Pan troglodytes
XP_001159977
468
50661
L215
Q
A
D
P
F
A
S
L
K
K
V
G
Q
D
S
Rhesus Macaque
Macaca mulatta
XP_001106724
490
53058
S236
E
Q
A
D
P
F
A
S
L
K
K
V
G
Q
D
Dog
Lupus familis
XP_854950
467
50519
L214
Q
A
D
P
F
A
S
L
K
K
V
G
Q
D
S
Cat
Felis silvestris
Mouse
Mus musculus
P70187
490
52958
S236
E
Q
A
D
P
F
A
S
L
K
K
V
G
Q
D
Rat
Rattus norvegicus
B2RYH9
507
54917
S246
K
Q
A
D
P
F
A
S
L
K
K
V
G
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512475
466
50593
K213
A
D
P
F
A
S
L
K
K
V
G
Q
D
S
I
Chicken
Gallus gallus
NP_001034410
492
52978
S236
E
Q
A
D
P
F
A
S
L
R
K
V
G
Q
D
Frog
Xenopus laevis
NP_001085612
484
52328
D231
P
I
S
W
E
Q
A
D
P
F
A
S
L
K
K
Zebra Danio
Brachydanio rerio
NP_955878
493
53097
S236
E
Q
A
D
P
F
A
S
L
R
K
V
G
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097489
705
75288
A452
E
Q
A
D
P
F
L
A
L
R
K
V
G
T
D
Honey Bee
Apis mellifera
XP_624637
518
55806
K235
D
P
F
A
Y
L
G
K
V
G
K
D
H
T
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780651
530
56878
Y264
Q
Y
S
C
M
F
L
Y
L
R
T
V
G
K
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
99.5
94.9
N.A.
99.1
70
N.A.
85.3
80.8
92
82.3
N.A.
41.5
59.8
N.A.
58.4
Protein Similarity:
100
95
99.8
95.3
N.A.
100
79.6
N.A.
89.1
90
94.6
90.6
N.A.
52.3
74.5
N.A.
71.7
P-Site Identity:
100
6.6
100
6.6
N.A.
100
86.6
N.A.
0
93.3
6.6
93.3
N.A.
73.3
6.6
N.A.
26.6
P-Site Similarity:
100
20
100
20
N.A.
100
100
N.A.
0
100
20
100
N.A.
86.6
20
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
16
54
8
8
16
54
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
16
54
0
0
0
8
0
0
0
8
8
16
54
% D
% Glu:
47
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
8
16
62
0
0
0
8
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
8
0
0
8
8
16
62
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
16
% I
% Lys:
8
0
0
0
0
0
0
16
24
47
62
0
0
24
8
% K
% Leu:
0
0
0
0
0
8
24
16
62
0
0
0
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
8
16
54
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
24
54
0
0
0
8
0
0
0
0
0
8
16
39
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
31
0
0
0
0
0
% R
% Ser:
0
0
16
0
0
8
16
47
0
0
0
8
0
8
16
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
0
0
16
0
% T
% Val:
0
0
0
0
0
0
0
0
8
8
16
62
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
8
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _