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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIAT1 All Species: 10.3
Human Site: S415 Identified Species: 18.89
UniProt: Q96MC6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96MC6 NP_149044.2 490 53027 S415 T D L G T N T S P Q H H F E Q
Chimpanzee Pan troglodytes XP_001159977 468 50661 P394 D L G T N T S P Q H H F E Q N
Rhesus Macaque Macaca mulatta XP_001106724 490 53058 S415 T D L G T N T S P Q H H F E Q
Dog Lupus familis XP_854950 467 50519 P393 D L G T N T S P Q H H F E Q N
Cat Felis silvestris
Mouse Mus musculus P70187 490 52958 S415 T D L G T N T S P Q H H F E Q
Rat Rattus norvegicus B2RYH9 507 54917 Q425 D S D N D P L Q G A F I P G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512475 466 50593 H392 L G A N P S P H H H S Q Q N S
Chicken Gallus gallus NP_001034410 492 52978 P415 T L G K A S K P N M A N P T D
Frog Xenopus laevis NP_001085612 484 52328 E410 P I T E T E H E G K M P V H K
Zebra Danio Brachydanio rerio NP_955878 493 53097 P415 S P E K G V K P N M A N P T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097489 705 75288 T631 K S S G S R A T N V E K I S Q
Honey Bee Apis mellifera XP_624637 518 55806 K414 S P L E E N N K T G T A T Q H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780651 530 56878 G443 D G G D G G G G G G G E E G G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95 99.5 94.9 N.A. 99.1 70 N.A. 85.3 80.8 92 82.3 N.A. 41.5 59.8 N.A. 58.4
Protein Similarity: 100 95 99.8 95.3 N.A. 100 79.6 N.A. 89.1 90 94.6 90.6 N.A. 52.3 74.5 N.A. 71.7
P-Site Identity: 100 6.6 100 6.6 N.A. 100 0 N.A. 0 6.6 6.6 0 N.A. 13.3 13.3 N.A. 0
P-Site Similarity: 100 20 100 20 N.A. 100 0 N.A. 6.6 20 20 13.3 N.A. 26.6 26.6 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 8 0 8 0 0 8 16 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 31 24 8 8 8 0 0 0 0 0 0 0 0 0 16 % D
% Glu: 0 0 8 16 8 8 0 8 0 0 8 8 24 24 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 16 24 0 0 % F
% Gly: 0 16 31 31 16 8 8 8 24 16 8 0 0 16 8 % G
% His: 0 0 0 0 0 0 8 8 8 24 39 24 0 8 8 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 8 8 0 0 % I
% Lys: 8 0 0 16 0 0 16 8 0 8 0 8 0 0 8 % K
% Leu: 8 24 31 0 0 0 8 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 16 8 0 0 0 0 % M
% Asn: 0 0 0 16 16 31 8 0 24 0 0 16 0 8 16 % N
% Pro: 8 16 0 0 8 8 8 31 24 0 0 8 24 0 8 % P
% Gln: 0 0 0 0 0 0 0 8 16 24 0 8 8 24 31 % Q
% Arg: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % R
% Ser: 16 16 8 0 8 16 16 24 0 0 8 0 0 8 8 % S
% Thr: 31 0 8 16 31 16 24 8 8 0 8 0 8 16 0 % T
% Val: 0 0 0 0 0 8 0 0 0 8 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _