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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIAT1
All Species:
16.97
Human Site:
S458
Identified Species:
31.11
UniProt:
Q96MC6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MC6
NP_149044.2
490
53027
S458
H
T
N
L
S
L
R
S
S
S
W
R
K
H
C
Chimpanzee
Pan troglodytes
XP_001159977
468
50661
S437
T
N
L
S
L
R
S
S
S
W
R
K
H
C
G
Rhesus Macaque
Macaca mulatta
XP_001106724
490
53058
S458
H
T
N
L
S
L
R
S
S
S
W
R
K
H
C
Dog
Lupus familis
XP_854950
467
50519
S436
T
N
L
S
L
R
S
S
S
W
R
K
H
C
G
Cat
Felis silvestris
Mouse
Mus musculus
P70187
490
52958
S458
H
T
N
L
S
L
R
S
S
S
W
R
K
H
C
Rat
Rattus norvegicus
B2RYH9
507
54917
S468
Q
K
H
N
N
S
I
S
G
S
L
S
T
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512475
466
50593
N435
N
L
N
V
R
S
G
N
W
K
K
H
C
G
G
Chicken
Gallus gallus
NP_001034410
492
52978
S458
E
H
N
L
T
L
R
S
G
S
H
K
K
H
N
Frog
Xenopus laevis
NP_001085612
484
52328
N453
I
P
E
H
T
N
L
N
I
R
S
G
S
W
K
Zebra Danio
Brachydanio rerio
NP_955878
493
53097
R458
E
H
N
G
L
N
L
R
P
G
S
Y
K
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097489
705
75288
R674
T
S
T
L
E
K
K
R
A
S
L
D
V
Q
Y
Honey Bee
Apis mellifera
XP_624637
518
55806
E457
L
V
A
A
F
I
P
E
S
N
T
M
P
T
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780651
530
56878
S486
L
P
N
V
Q
E
P
S
A
A
P
P
Q
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
99.5
94.9
N.A.
99.1
70
N.A.
85.3
80.8
92
82.3
N.A.
41.5
59.8
N.A.
58.4
Protein Similarity:
100
95
99.8
95.3
N.A.
100
79.6
N.A.
89.1
90
94.6
90.6
N.A.
52.3
74.5
N.A.
71.7
P-Site Identity:
100
13.3
100
13.3
N.A.
100
13.3
N.A.
6.6
53.3
0
13.3
N.A.
13.3
6.6
N.A.
13.3
P-Site Similarity:
100
20
100
20
N.A.
100
26.6
N.A.
26.6
66.6
13.3
13.3
N.A.
33.3
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
0
0
0
16
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
16
24
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
16
0
8
0
8
8
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
8
0
16
8
0
8
0
8
31
% G
% His:
24
16
8
8
0
0
0
0
0
0
8
8
16
31
8
% H
% Ile:
8
0
0
0
0
8
8
0
8
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
8
8
0
0
8
8
24
39
8
8
% K
% Leu:
16
8
16
39
24
31
16
0
0
0
16
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
8
16
54
8
8
16
0
16
0
8
0
0
0
0
8
% N
% Pro:
0
16
0
0
0
0
16
0
8
0
8
8
8
8
16
% P
% Gln:
8
0
0
0
8
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
8
16
31
16
0
8
16
24
0
0
0
% R
% Ser:
0
8
0
16
24
16
16
62
47
47
16
8
8
8
0
% S
% Thr:
24
24
8
0
16
0
0
0
0
0
8
0
8
8
0
% T
% Val:
0
8
0
16
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
16
24
0
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _