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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIAT1 All Species: 11.82
Human Site: S459 Identified Species: 21.67
UniProt: Q96MC6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96MC6 NP_149044.2 490 53027 S459 T N L S L R S S S W R K H C G
Chimpanzee Pan troglodytes XP_001159977 468 50661 S438 N L S L R S S S W R K H C G S
Rhesus Macaque Macaca mulatta XP_001106724 490 53058 S459 T N L S L R S S S W R K H C G
Dog Lupus familis XP_854950 467 50519 S437 N L S L R S S S W R K H C G S
Cat Felis silvestris
Mouse Mus musculus P70187 490 52958 S459 T N L S L R S S S W R K H C G
Rat Rattus norvegicus B2RYH9 507 54917 G469 K H N N S I S G S L S T P P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512475 466 50593 W436 L N V R S G N W K K H C G G S
Chicken Gallus gallus NP_001034410 492 52978 G459 H N L T L R S G S H K K H N N
Frog Xenopus laevis NP_001085612 484 52328 I454 P E H T N L N I R S G S W K K
Zebra Danio Brachydanio rerio NP_955878 493 53097 P459 H N G L N L R P G S Y K K H N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097489 705 75288 A675 S T L E K K R A S L D V Q Y E
Honey Bee Apis mellifera XP_624637 518 55806 S458 V A A F I P E S N T M P T G P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780651 530 56878 A487 P N V Q E P S A A P P Q S P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95 99.5 94.9 N.A. 99.1 70 N.A. 85.3 80.8 92 82.3 N.A. 41.5 59.8 N.A. 58.4
Protein Similarity: 100 95 99.8 95.3 N.A. 100 79.6 N.A. 89.1 90 94.6 90.6 N.A. 52.3 74.5 N.A. 71.7
P-Site Identity: 100 13.3 100 13.3 N.A. 100 13.3 N.A. 6.6 53.3 0 13.3 N.A. 13.3 6.6 N.A. 13.3
P-Site Similarity: 100 20 100 20 N.A. 100 26.6 N.A. 20 66.6 13.3 13.3 N.A. 33.3 20 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 8 0 0 0 0 16 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 16 24 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % D
% Glu: 0 8 0 8 8 0 8 0 0 0 0 0 0 0 16 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 0 8 0 16 8 0 8 0 8 31 24 % G
% His: 16 8 8 0 0 0 0 0 0 8 8 16 31 8 0 % H
% Ile: 0 0 0 0 8 8 0 8 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 8 8 0 0 8 8 24 39 8 8 8 % K
% Leu: 8 16 39 24 31 16 0 0 0 16 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % M
% Asn: 16 54 8 8 16 0 16 0 8 0 0 0 0 8 16 % N
% Pro: 16 0 0 0 0 16 0 8 0 8 8 8 8 16 8 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 8 8 0 0 % Q
% Arg: 0 0 0 8 16 31 16 0 8 16 24 0 0 0 0 % R
% Ser: 8 0 16 24 16 16 62 47 47 16 8 8 8 0 31 % S
% Thr: 24 8 0 16 0 0 0 0 0 8 0 8 8 0 0 % T
% Val: 8 0 16 0 0 0 0 0 0 0 0 8 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 16 24 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _