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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIAT1
All Species:
9.09
Human Site:
T406
Identified Species:
16.67
UniProt:
Q96MC6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MC6
NP_149044.2
490
53027
T406
E
L
K
E
L
P
I
T
G
T
D
L
G
T
N
Chimpanzee
Pan troglodytes
XP_001159977
468
50661
G385
L
K
E
L
P
I
T
G
T
D
L
G
T
N
T
Rhesus Macaque
Macaca mulatta
XP_001106724
490
53058
T406
E
L
K
E
L
P
I
T
G
T
D
L
G
T
N
Dog
Lupus familis
XP_854950
467
50519
G384
L
K
E
L
P
M
T
G
T
D
L
G
T
N
T
Cat
Felis silvestris
Mouse
Mus musculus
P70187
490
52958
T406
E
L
K
E
L
P
I
T
G
T
D
L
G
T
N
Rat
Rattus norvegicus
B2RYH9
507
54917
K416
E
L
N
E
L
G
P
K
L
D
S
D
N
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512475
466
50593
P383
N
E
L
P
I
T
E
P
D
L
G
A
N
P
S
Chicken
Gallus gallus
NP_001034410
492
52978
V406
E
L
N
E
M
A
E
V
E
T
L
G
K
A
S
Frog
Xenopus laevis
NP_001085612
484
52328
E401
I
F
H
V
E
L
N
E
L
P
I
T
E
T
E
Zebra Danio
Brachydanio rerio
NP_955878
493
53097
A406
E
L
S
E
M
D
P
A
E
S
P
E
K
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097489
705
75288
H622
L
N
D
D
H
D
S
H
A
K
S
S
G
S
R
Honey Bee
Apis mellifera
XP_624637
518
55806
K405
N
S
P
S
L
P
A
K
P
S
P
L
E
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780651
530
56878
G434
G
K
D
G
G
S
G
G
G
D
G
G
D
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
99.5
94.9
N.A.
99.1
70
N.A.
85.3
80.8
92
82.3
N.A.
41.5
59.8
N.A.
58.4
Protein Similarity:
100
95
99.8
95.3
N.A.
100
79.6
N.A.
89.1
90
94.6
90.6
N.A.
52.3
74.5
N.A.
71.7
P-Site Identity:
100
0
100
0
N.A.
100
26.6
N.A.
0
26.6
6.6
20
N.A.
6.6
26.6
N.A.
6.6
P-Site Similarity:
100
6.6
100
6.6
N.A.
100
26.6
N.A.
13.3
40
6.6
33.3
N.A.
20
33.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
8
8
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
16
8
0
16
0
0
8
31
24
8
8
8
0
% D
% Glu:
47
8
16
47
8
0
16
8
16
0
0
8
16
8
8
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
8
8
8
24
31
0
16
31
31
16
8
% G
% His:
0
0
8
0
8
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
8
8
24
0
0
0
8
0
0
0
0
% I
% Lys:
0
24
24
0
0
0
0
16
0
8
0
0
16
0
0
% K
% Leu:
24
47
8
16
39
8
0
0
16
8
24
31
0
0
0
% L
% Met:
0
0
0
0
16
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
16
8
16
0
0
0
8
0
0
0
0
0
16
16
31
% N
% Pro:
0
0
8
8
16
31
16
8
8
8
16
0
0
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
8
8
8
0
8
8
0
0
16
16
8
0
8
16
% S
% Thr:
0
0
0
0
0
8
16
24
16
31
0
8
16
31
16
% T
% Val:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _