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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf66
All Species:
28.48
Human Site:
T236
Identified Species:
69.63
UniProt:
Q96MD2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MD2
NP_689653.3
445
50415
T236
I
F
E
K
Q
R
E
T
K
K
H
L
F
G
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116875
445
50376
T236
I
F
E
K
Q
R
E
T
K
K
H
L
F
G
G
Dog
Lupus familis
XP_531657
445
50413
T236
I
F
E
K
Q
R
E
T
K
K
H
L
F
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1I3
445
50237
T236
T
F
E
K
Q
R
E
T
K
K
H
L
F
G
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521346
418
46566
K220
L
F
G
G
Q
S
Q
K
A
V
Q
P
P
H
L
Chicken
Gallus gallus
XP_416063
446
50573
T237
I
F
E
K
Q
R
E
T
K
K
H
L
F
G
G
Frog
Xenopus laevis
Q6IR80
442
50506
T235
I
F
E
K
Q
K
E
T
K
K
H
L
F
G
G
Zebra Danio
Brachydanio rerio
Q1L8F9
449
51149
T239
V
F
E
R
Q
R
E
T
R
K
H
L
F
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624797
405
46699
T207
M
A
L
Y
G
A
Q
T
R
M
S
A
W
E
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797380
335
37612
Q137
L
L
A
H
L
C
E
Q
L
S
H
F
I
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
96.8
N.A.
94.3
N.A.
N.A.
69.6
93
81.8
74.8
N.A.
N.A.
32.1
N.A.
30.1
Protein Similarity:
100
N.A.
100
98.6
N.A.
96.4
N.A.
N.A.
80.6
97
90.5
87.9
N.A.
N.A.
54.1
N.A.
45.8
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
13.3
100
93.3
80
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
N.A.
N.A.
26.6
100
100
100
N.A.
N.A.
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
0
10
0
0
10
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
70
0
0
0
80
0
0
0
0
0
0
20
0
% E
% Phe:
0
80
0
0
0
0
0
0
0
0
0
10
70
0
0
% F
% Gly:
0
0
10
10
10
0
0
0
0
0
0
0
0
70
70
% G
% His:
0
0
0
10
0
0
0
0
0
0
80
0
0
10
0
% H
% Ile:
50
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
0
0
60
0
10
0
10
60
70
0
0
0
0
0
% K
% Leu:
20
10
10
0
10
0
0
0
10
0
0
70
0
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% P
% Gln:
0
0
0
0
80
0
20
10
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
10
0
60
0
0
20
0
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
10
0
0
0
10
10
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
80
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _