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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf66
All Species:
28.79
Human Site:
Y171
Identified Species:
70.37
UniProt:
Q96MD2
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MD2
NP_689653.3
445
50415
Y171
L
D
A
I
M
K
K
Y
S
S
R
F
H
H
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116875
445
50376
Y171
L
D
A
I
L
K
K
Y
S
S
R
F
H
H
P
Dog
Lupus familis
XP_531657
445
50413
Y171
L
D
T
I
L
K
K
Y
S
S
R
F
H
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1I3
445
50237
Y171
L
D
T
I
L
R
K
Y
S
S
R
F
H
H
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521346
418
46566
G159
I
L
S
P
L
A
S
G
F
Q
L
E
V
D
V
Chicken
Gallus gallus
XP_416063
446
50573
Y172
L
E
S
I
L
K
K
Y
S
S
R
F
H
H
P
Frog
Xenopus laevis
Q6IR80
442
50506
Y170
L
E
A
I
L
K
K
Y
S
S
R
F
H
H
P
Zebra Danio
Brachydanio rerio
Q1L8F9
449
51149
Y174
L
D
S
I
L
Q
K
Y
S
S
R
F
H
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624797
405
46699
L146
K
S
M
K
Y
Q
E
L
L
Q
C
I
E
G
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_797380
335
37612
Y76
L
N
A
A
E
K
S
Y
T
S
L
T
F
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.8
96.8
N.A.
94.3
N.A.
N.A.
69.6
93
81.8
74.8
N.A.
N.A.
32.1
N.A.
30.1
Protein Similarity:
100
N.A.
100
98.6
N.A.
96.4
N.A.
N.A.
80.6
97
90.5
87.9
N.A.
N.A.
54.1
N.A.
45.8
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
80
N.A.
N.A.
0
80
86.6
80
N.A.
N.A.
0
N.A.
33.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
N.A.
N.A.
20
100
100
100
N.A.
N.A.
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
40
10
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
50
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
20
0
0
10
0
10
0
0
0
0
10
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
70
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
70
70
0
% H
% Ile:
10
0
0
70
0
0
0
0
0
0
0
10
0
0
10
% I
% Lys:
10
0
0
10
0
60
70
0
0
0
0
0
0
0
0
% K
% Leu:
80
10
0
0
70
0
0
10
10
0
20
0
0
10
0
% L
% Met:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
70
% P
% Gln:
0
0
0
0
0
20
0
0
0
20
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
0
0
70
0
0
0
0
% R
% Ser:
0
10
30
0
0
0
20
0
70
80
0
0
0
0
0
% S
% Thr:
0
0
20
0
0
0
0
0
10
0
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _