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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXL18 All Species: 1.82
Human Site: T279 Identified Species: 10
UniProt: Q96ME1 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96ME1 NP_079239.3 805 88341 T279 S F A E S G A T K N L L D S M
Chimpanzee Pan troglodytes XP_518952 749 82453 L261 N V P H Y Q N L R V F Y A R L
Rhesus Macaque Macaca mulatta XP_001107854 748 82141 N259 S N V P H Y Q N L R V F Y A R
Dog Lupus familis XP_546999 828 90486 T282 L S G E C K A T L S R V R E L
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001012804 711 79274 N223 S N V P H Y Q N L R V F Y A R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 84.7 76 N.A. N.A. N.A. N.A. N.A. 66.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 87.1 86.9 82.2 N.A. N.A. N.A. N.A. N.A. 78.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 6.6 20 N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 20 40 N.A. N.A. N.A. N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 20 0 0 0 40 0 0 0 0 0 20 40 0 % A
% Cys: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % D
% Glu: 0 0 0 40 0 0 0 0 0 0 0 0 0 20 0 % E
% Phe: 0 20 0 0 0 0 0 0 0 0 20 40 0 0 0 % F
% Gly: 0 0 20 0 0 20 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 20 40 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 20 0 0 20 0 0 0 0 0 0 % K
% Leu: 20 0 0 0 0 0 0 20 60 0 20 20 0 0 40 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 20 % M
% Asn: 20 40 0 0 0 0 20 40 0 20 0 0 0 0 0 % N
% Pro: 0 0 20 40 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 20 40 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 20 40 20 0 20 20 40 % R
% Ser: 60 20 0 0 20 0 0 0 0 20 0 0 0 20 0 % S
% Thr: 0 0 0 0 0 0 0 40 0 0 0 0 0 0 0 % T
% Val: 0 20 40 0 0 0 0 0 0 20 40 20 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 20 40 0 0 0 0 0 20 40 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _