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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEXIM2
All Species:
18.18
Human Site:
S169
Identified Species:
44.44
UniProt:
Q96MH2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MH2
NP_653209.1
286
32419
S169
H
G
I
S
H
P
G
S
S
G
E
S
E
A
G
Chimpanzee
Pan troglodytes
XP_001141303
308
35029
S191
H
G
I
S
H
P
G
S
S
G
E
S
E
A
G
Rhesus Macaque
Macaca mulatta
XP_001115288
286
32307
S169
H
G
I
S
H
P
G
S
S
G
E
S
E
A
G
Dog
Lupus familis
XP_848305
337
37746
S220
H
G
A
S
H
P
G
S
S
G
E
S
E
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3TVI4
313
35378
S168
H
G
P
S
H
S
G
S
G
G
E
N
E
A
G
Rat
Rattus norvegicus
Q5M9G1
356
40299
A226
T
G
L
Y
P
K
R
A
A
A
K
S
D
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4V7W3
285
32469
S167
N
S
S
Y
K
G
D
S
T
D
D
D
L
E
E
Zebra Danio
Brachydanio rerio
A5D8S8
319
36200
N191
D
T
A
S
E
D
E
N
F
E
A
E
E
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121823
423
47067
E184
D
L
D
Q
K
L
S
E
A
A
S
S
E
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792438
230
26777
N126
D
E
V
L
E
N
E
N
E
E
Y
L
V
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
97.5
68.5
N.A.
70.6
40.4
N.A.
N.A.
N.A.
41.6
39.5
N.A.
N.A.
23.3
N.A.
28.3
Protein Similarity:
100
92.8
98.5
74.4
N.A.
76
54.4
N.A.
N.A.
N.A.
55.9
52.6
N.A.
N.A.
35.7
N.A.
43
P-Site Identity:
100
100
100
93.3
N.A.
73.3
13.3
N.A.
N.A.
N.A.
6.6
13.3
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
80
46.6
N.A.
N.A.
N.A.
26.6
20
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
0
0
10
20
20
10
0
0
50
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
0
10
0
0
10
10
0
0
10
10
10
10
20
10
% D
% Glu:
0
10
0
0
20
0
20
10
10
20
50
10
70
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
60
0
0
0
10
50
0
10
50
0
0
0
0
50
% G
% His:
50
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
20
10
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
10
10
10
0
10
0
0
0
0
0
10
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
10
0
20
0
0
0
10
0
0
10
% N
% Pro:
0
0
10
0
10
40
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% R
% Ser:
0
10
10
60
0
10
10
60
40
0
10
60
0
0
0
% S
% Thr:
10
10
0
0
0
0
0
0
10
0
0
0
0
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
20
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _