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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEXIM2
All Species:
17.88
Human Site:
T261
Identified Species:
43.7
UniProt:
Q96MH2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MH2
NP_653209.1
286
32419
T261
A
E
V
Q
R
L
R
T
E
N
Q
R
L
R
Q
Chimpanzee
Pan troglodytes
XP_001141303
308
35029
T283
A
E
V
Q
R
L
R
T
E
N
Q
R
L
R
Q
Rhesus Macaque
Macaca mulatta
XP_001115288
286
32307
T261
A
E
V
E
R
L
R
T
E
N
Q
R
L
R
Q
Dog
Lupus familis
XP_848305
337
37746
T312
A
E
V
E
R
L
R
T
E
N
L
R
L
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q3TVI4
313
35378
T260
A
E
V
E
R
L
R
T
E
N
Q
R
L
R
Q
Rat
Rattus norvegicus
Q5M9G1
356
40299
A331
L
E
L
D
R
L
R
A
E
N
R
Q
L
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4V7W3
285
32469
E268
V
E
L
E
K
L
K
E
E
N
Q
R
L
L
Q
Zebra Danio
Brachydanio rerio
A5D8S8
319
36200
A296
V
E
V
E
K
L
R
A
E
N
N
E
L
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121823
423
47067
R317
Q
Q
N
E
Q
L
K
R
E
N
E
L
L
R
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792438
230
26777
E216
E
K
V
E
K
L
K
E
E
N
K
R
L
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
97.5
68.5
N.A.
70.6
40.4
N.A.
N.A.
N.A.
41.6
39.5
N.A.
N.A.
23.3
N.A.
28.3
Protein Similarity:
100
92.8
98.5
74.4
N.A.
76
54.4
N.A.
N.A.
N.A.
55.9
52.6
N.A.
N.A.
35.7
N.A.
43
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
46.6
N.A.
N.A.
N.A.
53.3
46.6
N.A.
N.A.
33.3
N.A.
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
100
66.6
N.A.
N.A.
N.A.
80
60
N.A.
N.A.
66.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
0
0
0
20
0
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
80
0
70
0
0
0
20
100
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
30
0
30
0
0
0
10
0
0
0
0
% K
% Leu:
10
0
20
0
0
100
0
0
0
0
10
10
100
30
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
100
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
10
0
20
10
0
0
0
0
0
50
10
0
0
60
% Q
% Arg:
0
0
0
0
60
0
70
10
0
0
10
70
0
70
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
50
0
0
0
0
0
0
20
% T
% Val:
20
0
70
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _