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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HEXIM2
All Species:
34.85
Human Site:
Y217
Identified Species:
85.19
UniProt:
Q96MH2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MH2
NP_653209.1
286
32419
Y217
K
Q
E
L
V
R
D
Y
L
E
L
E
K
R
L
Chimpanzee
Pan troglodytes
XP_001141303
308
35029
Y239
K
Q
E
L
V
R
D
Y
L
E
L
E
K
R
L
Rhesus Macaque
Macaca mulatta
XP_001115288
286
32307
Y217
K
Q
E
L
V
R
D
Y
L
E
L
E
K
R
L
Dog
Lupus familis
XP_848305
337
37746
Y268
K
Q
E
L
V
R
D
Y
L
D
L
E
R
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3TVI4
313
35378
Y216
K
Q
E
L
V
R
D
Y
L
D
L
E
R
R
L
Rat
Rattus norvegicus
Q5M9G1
356
40299
Y288
K
Q
E
L
I
K
E
Y
L
E
L
E
K
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4V7W3
285
32469
Y221
K
Q
D
L
I
K
E
Y
L
E
L
E
K
C
L
Zebra Danio
Brachydanio rerio
A5D8S8
319
36200
Y248
K
Q
E
L
V
R
E
Y
L
E
L
E
K
C
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121823
423
47067
Y256
K
S
E
L
I
Q
E
Y
L
Q
L
E
A
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792438
230
26777
R173
S
E
L
E
Q
I
L
R
P
G
S
G
G
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
97.5
68.5
N.A.
70.6
40.4
N.A.
N.A.
N.A.
41.6
39.5
N.A.
N.A.
23.3
N.A.
28.3
Protein Similarity:
100
92.8
98.5
74.4
N.A.
76
54.4
N.A.
N.A.
N.A.
55.9
52.6
N.A.
N.A.
35.7
N.A.
43
P-Site Identity:
100
100
100
86.6
N.A.
86.6
73.3
N.A.
N.A.
N.A.
66.6
80
N.A.
N.A.
46.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
N.A.
93.3
93.3
N.A.
N.A.
86.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% C
% Asp:
0
0
10
0
0
0
50
0
0
20
0
0
0
0
0
% D
% Glu:
0
10
80
10
0
0
40
0
0
60
0
90
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
10
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
30
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
90
0
0
0
0
20
0
0
0
0
0
0
60
10
0
% K
% Leu:
0
0
10
90
0
0
10
0
90
0
90
0
0
0
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
80
0
0
10
10
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
60
0
10
0
0
0
0
20
50
0
% R
% Ser:
10
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
90
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _