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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM68
All Species:
17.88
Human Site:
S317
Identified Species:
39.33
UniProt:
Q96MH6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MH6
NP_689630.1
324
37425
S317
R
I
P
G
N
I
M
S
A
L
L
E
R
F
H
Chimpanzee
Pan troglodytes
XP_519763
324
37405
S317
R
I
P
G
N
I
M
S
A
L
L
E
R
F
H
Rhesus Macaque
Macaca mulatta
XP_001084561
324
37392
S317
R
I
P
G
N
I
M
S
A
L
L
E
R
F
H
Dog
Lupus familis
XP_544087
330
38145
S317
R
I
P
G
N
I
M
S
A
L
L
E
R
F
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9D850
329
37792
S316
R
I
P
G
N
I
R
S
A
L
L
D
R
F
H
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514254
329
37950
R316
R
I
P
G
N
I
L
R
A
L
L
E
R
F
H
Chicken
Gallus gallus
Q5ZJD8
332
37950
R319
K
I
P
G
N
I
L
R
A
L
M
E
R
F
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956786
331
37988
R318
K
I
P
G
N
I
L
R
A
L
L
E
R
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096954
323
37682
L305
R
L
P
G
S
I
L
L
A
L
L
D
R
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023446
353
41188
R322
R
L
P
G
S
V
W
R
G
I
A
Q
R
W
S
Sea Urchin
Strong. purpuratus
XP_782190
339
38859
R325
K
I
P
G
S
I
R
R
A
F
L
E
R
F
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.7
95.7
N.A.
91.4
N.A.
N.A.
83.8
59
N.A.
67.6
N.A.
45.6
N.A.
41
41
Protein Similarity:
100
100
100
97.5
N.A.
95.7
N.A.
N.A.
92.7
73.4
N.A.
83.3
N.A.
64.8
N.A.
59.7
61
P-Site Identity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
86.6
66.6
N.A.
73.3
N.A.
53.3
N.A.
26.6
60
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
93.3
86.6
N.A.
86.6
N.A.
80
N.A.
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
91
0
10
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
73
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
82
0
% F
% Gly:
0
0
0
100
0
0
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
55
% H
% Ile:
0
82
0
0
0
91
0
0
0
10
0
0
0
0
0
% I
% Lys:
28
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
19
0
0
0
0
37
10
0
82
82
0
0
10
0
% L
% Met:
0
0
0
0
0
0
37
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
73
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
19
% Q
% Arg:
73
0
0
0
0
0
19
46
0
0
0
0
100
0
0
% R
% Ser:
0
0
0
0
28
0
0
46
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _