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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM65C
All Species:
10.3
Human Site:
S378
Identified Species:
25.19
UniProt:
Q96MK2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MK2
NP_543019.2
946
105290
S378
L
G
G
P
R
A
T
S
I
L
S
Y
L
S
D
Chimpanzee
Pan troglodytes
XP_001167914
946
105264
S378
L
G
G
P
R
A
T
S
I
L
S
Y
L
S
D
Rhesus Macaque
Macaca mulatta
XP_001101354
691
76709
A196
D
M
W
L
I
E
G
A
L
E
V
H
L
G
E
Dog
Lupus familis
XP_543049
593
66165
Y98
I
Q
Q
A
E
L
D
Y
L
S
G
R
H
K
D
Cat
Felis silvestris
Mouse
Mus musculus
A1L3T7
938
104142
S378
L
G
G
P
K
A
T
S
I
L
G
Y
L
S
D
Rat
Rattus norvegicus
Q4FZU8
1217
131713
E380
T
A
W
S
L
S
S
E
S
S
D
D
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506522
1149
123542
E364
A
A
W
S
L
S
S
E
S
S
D
D
S
S
S
Chicken
Gallus gallus
Q5F3L9
602
66878
R107
T
A
Q
L
K
D
M
R
R
N
S
R
L
G
V
Frog
Xenopus laevis
NP_001089796
313
36365
Zebra Danio
Brachydanio rerio
Q5EB20
978
109822
S375
F
S
I
G
S
R
E
S
R
G
V
S
L
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
70.3
54.4
N.A.
76.2
29.5
N.A.
31.7
31.3
22.7
38.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.1
71.2
57.1
N.A.
84.3
42.8
N.A.
44
43.3
28.3
56.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
6.6
N.A.
86.6
6.6
N.A.
6.6
13.3
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
33.3
20
N.A.
93.3
20
N.A.
20
20
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
30
0
10
0
30
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
10
10
0
0
0
20
20
0
0
40
% D
% Glu:
0
0
0
0
10
10
10
20
0
10
0
0
0
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
30
30
10
0
0
10
0
0
10
20
0
0
20
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% H
% Ile:
10
0
10
0
10
0
0
0
30
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
20
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
30
0
0
20
20
10
0
0
20
30
0
0
60
10
0
% L
% Met:
0
10
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
20
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
20
10
0
10
20
0
0
20
0
0
0
% R
% Ser:
0
10
0
20
10
20
20
40
20
30
30
10
20
50
30
% S
% Thr:
20
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
10
% V
% Trp:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
30
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _