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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM65C All Species: 10
Human Site: S887 Identified Species: 24.44
UniProt: Q96MK2 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96MK2 NP_543019.2 946 105290 S887 K H L K G I E S I D Q T A S L
Chimpanzee Pan troglodytes XP_001167914 946 105264 S887 K H L K G I E S I D Q I A S L
Rhesus Macaque Macaca mulatta XP_001101354 691 76709 K635 V C K A L L Q K L A S P N L S
Dog Lupus familis XP_543049 593 66165 L537 T Q P Q L R E L E F Q V L G F
Cat Felis silvestris
Mouse Mus musculus A1L3T7 938 104142 S880 Q Q L G G I E S C E Q I V S L
Rat Rattus norvegicus Q4FZU8 1217 131713 G1159 G C I K A P E G I E P L V Y L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506522 1149 123542 G1091 G C L R A P E G I E P L V Y L
Chicken Gallus gallus Q5F3L9 602 66878 K546 S G E S E G Y K S Y L D G S I
Frog Xenopus laevis NP_001089796 313 36365 L257 E R M F I P N L C E N F E I K
Zebra Danio Brachydanio rerio Q5EB20 978 109822 S920 K S L K A S E S A E Q V A E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 70.3 54.4 N.A. 76.2 29.5 N.A. 31.7 31.3 22.7 38.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.1 71.2 57.1 N.A. 84.3 42.8 N.A. 44 43.3 28.3 56.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 0 13.3 N.A. 53.3 26.6 N.A. 26.6 6.6 0 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 93.3 20 20 N.A. 66.6 40 N.A. 40 13.3 20 60 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 30 0 0 0 10 10 0 0 30 0 0 % A
% Cys: 0 30 0 0 0 0 0 0 20 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 20 0 10 0 0 0 % D
% Glu: 10 0 10 0 10 0 70 0 10 50 0 0 10 10 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 10 0 10 0 0 10 % F
% Gly: 20 10 0 10 30 10 0 20 0 0 0 0 10 10 0 % G
% His: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 10 30 0 0 40 0 0 20 0 10 10 % I
% Lys: 30 0 10 40 0 0 0 20 0 0 0 0 0 0 10 % K
% Leu: 0 0 50 0 20 10 0 20 10 0 10 20 10 10 60 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 10 0 10 0 0 % N
% Pro: 0 0 10 0 0 30 0 0 0 0 20 10 0 0 0 % P
% Gln: 10 20 0 10 0 0 10 0 0 0 50 0 0 0 0 % Q
% Arg: 0 10 0 10 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 10 0 10 0 10 0 40 10 0 10 0 0 40 10 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % T
% Val: 10 0 0 0 0 0 0 0 0 0 0 20 30 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 10 0 0 0 20 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _