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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA12B
All Species:
22.12
Human Site:
S46
Identified Species:
54.07
UniProt:
Q96MM6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MM6
NP_443202.3
686
75688
S46
A
P
L
T
P
S
Q
S
P
K
P
E
V
R
A
Chimpanzee
Pan troglodytes
XP_514486
686
75615
S46
A
P
L
T
P
S
Q
S
P
K
P
E
V
R
A
Rhesus Macaque
Macaca mulatta
XP_001111342
686
75850
S46
A
P
L
T
P
S
Q
S
P
K
P
E
A
R
A
Dog
Lupus familis
XP_851446
742
81901
S108
A
P
L
T
P
S
Q
S
P
K
P
E
A
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZJ2
685
76101
S46
A
P
L
T
P
S
Q
S
P
K
P
E
A
R
A
Rat
Rattus norvegicus
NP_001100915
675
74812
I42
T
P
L
S
P
S
H
I
L
N
D
A
D
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512019
674
75027
V41
P
L
S
P
S
H
A
V
N
D
S
D
P
N
V
Chicken
Gallus gallus
XP_421779
670
74732
D45
V
K
D
S
D
A
E
D
A
V
E
Q
L
F
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036151
691
77339
S46
T
P
L
T
P
S
P
S
P
R
T
E
V
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780658
1340
145466
T710
A
I
N
S
L
P
A
T
P
I
P
V
S
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.8
88
N.A.
93.8
62.2
N.A.
61.8
61.9
N.A.
69.9
N.A.
N.A.
N.A.
N.A.
25.7
Protein Similarity:
100
99.8
98.8
89.7
N.A.
95.4
76.9
N.A.
77.1
77.1
N.A.
82.4
N.A.
N.A.
N.A.
N.A.
36.7
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
26.6
N.A.
0
0
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
33.3
N.A.
6.6
33.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
0
0
0
0
10
20
0
10
0
0
10
30
0
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
10
0
0
10
0
10
10
10
10
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
0
0
10
60
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
10
0
0
0
0
10
% I
% Lys:
0
10
0
0
0
0
0
0
0
50
0
0
0
0
0
% K
% Leu:
0
10
70
0
10
0
0
0
10
0
0
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
10
10
0
0
0
10
0
% N
% Pro:
10
70
0
10
70
10
10
0
70
0
60
0
10
20
10
% P
% Gln:
0
0
0
0
0
0
50
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
60
0
% R
% Ser:
0
0
10
30
10
70
0
60
0
0
10
0
10
0
0
% S
% Thr:
20
0
0
60
0
0
0
10
0
0
10
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
10
0
10
0
10
30
0
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _