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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA12B
All Species:
18.18
Human Site:
Y249
Identified Species:
44.44
UniProt:
Q96MM6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96MM6
NP_443202.3
686
75688
Y249
E
P
E
A
A
S
V
Y
C
R
K
L
R
L
H
Chimpanzee
Pan troglodytes
XP_514486
686
75615
Y249
E
P
E
A
A
S
V
Y
C
R
K
L
R
L
H
Rhesus Macaque
Macaca mulatta
XP_001111342
686
75850
Y249
E
P
E
A
A
S
V
Y
C
R
K
L
R
L
H
Dog
Lupus familis
XP_851446
742
81901
Y311
E
P
E
A
A
S
V
Y
C
R
K
L
R
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9CZJ2
685
76101
Y249
E
P
E
A
A
S
V
Y
C
R
K
L
R
L
H
Rat
Rattus norvegicus
NP_001100915
675
74812
I244
L
E
P
E
A
A
S
I
Y
C
R
K
L
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512019
674
75027
I243
L
E
P
E
A
A
S
I
Y
C
R
K
L
R
L
Chicken
Gallus gallus
XP_421779
670
74732
I240
L
E
P
E
A
A
S
I
Y
C
R
K
L
R
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036151
691
77339
C250
P
E
A
A
S
I
Y
C
R
K
L
R
L
H
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780658
1340
145466
A908
V
L
V
V
V
M
T
A
L
A
S
G
L
E
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.8
88
N.A.
93.8
62.2
N.A.
61.8
61.9
N.A.
69.9
N.A.
N.A.
N.A.
N.A.
25.7
Protein Similarity:
100
99.8
98.8
89.7
N.A.
95.4
76.9
N.A.
77.1
77.1
N.A.
82.4
N.A.
N.A.
N.A.
N.A.
36.7
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
20
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
60
80
30
0
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
50
30
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
50
40
50
30
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
50
% H
% Ile:
0
0
0
0
0
10
0
30
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
50
30
0
0
0
% K
% Leu:
30
10
0
0
0
0
0
0
10
0
10
50
50
50
30
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
50
30
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
10
50
30
10
50
30
0
% R
% Ser:
0
0
0
0
10
50
30
0
0
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% T
% Val:
10
0
10
10
10
0
50
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
50
30
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _