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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ROBO3 All Species: 15.76
Human Site: S1186 Identified Species: 34.67
UniProt: Q96MS0 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96MS0 NP_071765.2 1386 148209 S1186 R V P L G P S S P L S V S Q P
Chimpanzee Pan troglodytes XP_001144482 1395 153226 Y1193 L D E L T R A Y Q F D I A K Q
Rhesus Macaque Macaca mulatta XP_001106913 1300 139057 A1123 G I R E G R P A G S A A L P H
Dog Lupus familis XP_546425 1385 148148 S1187 R V P L G P S S P L S V S Q P
Cat Felis silvestris
Mouse Mus musculus Q9Z2I4 1366 146035 S1186 R V P L G P S S P L S V S Q P
Rat Rattus norvegicus O55005 1651 180729 T1310 R P I S P P H T Y G Y I S G P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512208 1575 172904 E1265 D D E D D E E E A L E I T R P
Chicken Gallus gallus XP_416674 1403 153767 Y1175 L D E L T R A Y Q F D I A K Q
Frog Xenopus laevis NP_001084250 1614 176716 T1272 R P I S P P H T Y G Y I S G P
Zebra Danio Brachydanio rerio Q7ZW34 1056 116184 L885 L G K K K R T L G N E T N M L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_726224 1429 155803 A1239 Q H P P Q L P A Y F A T T G P
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.9 90.9 90.3 N.A. 80.5 38.6 N.A. 40.7 42 39.2 20.3 N.A. 27.4 N.A. N.A. N.A.
Protein Similarity: 100 58.1 91.8 93.4 N.A. 85.9 53.4 N.A. 55.6 57 54 35.4 N.A. 42.2 N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 100 N.A. 100 26.6 N.A. 13.3 6.6 26.6 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 26.6 100 N.A. 100 40 N.A. 33.3 33.3 40 13.3 N.A. 40 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 19 19 10 0 19 10 19 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 28 0 10 10 0 0 0 0 0 19 0 0 0 0 % D
% Glu: 0 0 28 10 0 10 10 10 0 0 19 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0 % F
% Gly: 10 10 0 0 37 0 0 0 19 19 0 0 0 28 0 % G
% His: 0 10 0 0 0 0 19 0 0 0 0 0 0 0 10 % H
% Ile: 0 10 19 0 0 0 0 0 0 0 0 46 0 0 0 % I
% Lys: 0 0 10 10 10 0 0 0 0 0 0 0 0 19 0 % K
% Leu: 28 0 0 46 0 10 0 10 0 37 0 0 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % N
% Pro: 0 19 37 10 19 46 19 0 28 0 0 0 0 10 64 % P
% Gln: 10 0 0 0 10 0 0 0 19 0 0 0 0 28 19 % Q
% Arg: 46 0 10 0 0 37 0 0 0 0 0 0 0 10 0 % R
% Ser: 0 0 0 19 0 0 28 28 0 10 28 0 46 0 0 % S
% Thr: 0 0 0 0 19 0 10 19 0 0 0 19 19 0 0 % T
% Val: 0 28 0 0 0 0 0 0 0 0 0 28 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 19 28 0 19 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _